gene 700 words KG: MTERF1 2026-03-24
kind:genesection:genesstate:published
Contents

MTERF1 Gene - Mitochondrial Transcription Termination Factor 1

🧬 Gene Info
Gene SymbolMTERF1
Full NameMitochondrial Transcription Termination Factor 1
AliasesPage for MTERF1 Gene
Chromosome7q21.3
FunctionMTERF1 is a mitochondrial protein that regulates transcription of mitochondrial DNA (mtDNA)
Primary ExpressionHigh in brain, heart, skeletal muscle (mitochondrial)
Amino Acids399 aa
Exons2
UniProt IDP56183
NCBI Gene ID5101
Ensembl IDENSG00000138442
OMIM605350
GeneCardsMTERF1
Human Protein AtlasMTERF1
Associated DiseasesParkinson's Disease, Alzheimer's Disease, Mitochondrial Disorders
KG Connections6 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (15)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47

Related Analyses (11)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

Related Experiments (2)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (4)

Packard Center for ALS Research
institution · KG edge: regulates
TFAM Gene
gene · KG edge: regulates
REST Gene
gene · KG edge: regulates
Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (6 edges)

MTERF1 regulates Als
MTERF1 regulates Ms
REST regulates MTERF1
TFAM regulates MTERF1
MTDNA regulates MTERF1
MITOCHONDRIAL DNA regulates MTERF1