REST

Understanding Entity Pages

This page aggregates everything SciDEX knows about REST: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

REST is a gene implicated in neurodegeneration research. Key relationships include: regulates, activates, associated with. Associated with ALS, Aging, Als. Connected to 157 entities in the SciDEX knowledge graph.

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graph TD
    REST["REST"] -->|"protects against"| Dementia["Dementia"]
    REST["REST"] -->|"regulates"| OGDHL["OGDHL"]
    REST["REST"] -.->|"inhibits"| Alzheimer["Alzheimer"]
    REST["REST"] -.->|"inhibits"| Ms["Ms"]
    REST["REST"] -.->|"inhibits"| Als["Als"]
    REST["REST"] -.->|"inhibits"| Aging["Aging"]
    CD2AP["CD2AP"] -->|"activates"| REST["REST"]
    NRF2["NRF2"] -->|"activates"| REST["REST"]
    CLOCK["CLOCK"] -->|"regulates"| REST["REST"]
    GENES["GENES"] -->|"regulates"| REST["REST"]
    style REST fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0