concept

NEUROMYELITIS OPTICA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NEUROMYELITIS OPTICA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

23Connections

0Hypotheses

0Analyses

1Outgoing

22Incoming

0Experiments

0Debates

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Pathway Diagram

graph TD
    NEUROMYELITIS_OPTICA[NEUROMYELITIS OPTICA]
    NEUROMYELITIS_OPTICA -->|causes| Cognitive_Decline[Cognitive Decline]
    AQP4[AQP4] -.biomarker for.-> NEUROMYELITIS_OPTICA
    Chi3L1[Chi3L1] -.biomarker for.-> NEUROMYELITIS_OPTICA
    CHI3L1[CHI3L1] -.biomarker for.-> NEUROMYELITIS_OPTICA
    AQP4_AB[AQP4-AB] -->|causes| NEUROMYELITIS_OPTICA
    AQP4_ab[AQP4-ab] -->|causes| NEUROMYELITIS_OPTICA
    Neuroinflammation[Neuroinflammation] -->|causes| NEUROMYELITIS_OPTICA
    immune_tolerance[immune tolerance] -.protects against.-> NEUROMYELITIS_OPTICA
    B_Cells[B Cells] -->|involved_in| NEUROMYELITIS_OPTICA
    CR2_Crry[CR2-Crry] -->|treats| NEUROMYELITIS_OPTICA

Outgoing (1)

Target	Relation	Type	Str
Cognitive Decline	causes	phenotype	0.85

Incoming (22)

Source	Relation	Type	Str
AQP4	biomarker_for	protein	0.95
CHI3L1	biomarker_for	protein	0.90
AQP4-AB	causes	protein	0.90
Neuroinflammation	causes	process	0.90
AQP4	associated_with	protein	0.90
Chi3L1	biomarker_for	biomarker	0.90
AQP4-ab	causes	protein	0.90
AQP4	markers	gene	0.90
immune tolerance	protects_against	process	0.87
CR2-Crry	treats	compound	0.85
B Cells	protects_against	cell_type	0.85
B Cells	involved_in	cell_type	0.85
Microglia	contributes_to	cell_type	0.85
Satralizumab	treats	drug	0.80
Complement Cascade	causes	pathway	0.80
Inebilizumab	treats	drug	0.80
complement C3	mediates	protein	0.80
Eculizumab	treats	drug	0.80
AQP4	involved_in	protein	0.80
Tolerance	protects_against	process	0.80
Rituximab	treats	drug	0.70
AQP4	implicated_in	protein	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity