protein

P2RX5PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about P2RX5PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

The P2X5 receptor (P2X5R) is a member of the P2X family of ATP-gated ion channels, encoded by the P2RX5 gene.

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🔬 Protein Info

Gene Symbol	P2RX5PROTEIN
Protein Type	Channel
Function	is a member of the P2X family of ATP-gated ion channels, encoded by the P2RX5 gene.
Primary Expression	specific tissues including lymphoid organs, bladder, and selective neuronal populations
Amino Acids	422 aa
GeneCards	P2RX5PROTEIN
Human Protein Atlas	P2RX5PROTEIN
Subunit size	~422 amino acids
Ion selectivity	Non-selective cation channel
Permeability	Na⁺, K⁺, Ca²⁺
ATP EC₅₀	~10-30 μM
Desensitization	Slow
Associated Diseases	ALS, Inflammation
Interactions	PANX1, P2RY12, P2RX7, P2RX4, ADORA2B, P2RX1
KG Connections	45 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

P2X5 Receptor Protein

protein · 672 words

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Pathway Diagram

graph TD
    P2RX5PROTEIN["P2RX5PROTEIN"]
    neurodegeneration["neurodegeneration"]
    P2RX5PROTEIN -->|"implicated_in"| neurodegeneration
    style P2RX5PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found