Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PCTR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| Endothelial Glycocalyx | associated_with | process | 0.90 |
| Lung Inflammation | suppresses | process | 0.90 |
| ALX/SIRT1/NF-kappa B axis | modulates | pathway | 0.90 |
| Sepsis | protects_against | disease | 0.90 |
| Acute Lung Injury | treats | disease | 0.85 |
| Sepsis | treats | disease | 0.85 |
| ALX | activates | receptor | 0.80 |
| TNF | downregulates | protein | 0.80 |
| IL6 | downregulates | protein | 0.80 |
| IL1B | downregulates | protein | 0.80 |
| macrophage | expressed_in | cell_type | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||