Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ALX: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Anti-inflammatory Response | mediates | process | 0.87 |
| ANXA1 | binds | protein | 0.85 |
| pulmonary endothelial glycocalyx | regulates | process | 0.80 |
| Annexin A1 | interacts_with | protein | 0.80 |
| AMPK-mTOR Pathway | activates | pathway | 0.80 |
| SIRT1 | activates | protein | 0.80 |
| oxidative stress response | participates_in | pathway | 0.70 |
| stroke | regulates | disease | 0.60 |
| SIRT1 | regulates | gene | 0.60 |
| AMPK | regulates | gene | 0.60 |
| PI3K-AKT-mTOR signaling | participates_in | pathway | 0.60 |
| AMPK | activates | gene | 0.60 |
| NF-kB signaling | participates_in | pathway | 0.60 |
| endothelial cells | expressed_in | cell_type | 0.60 |
| microglia | expressed_in | cell_type | 0.55 |
| macrophages | expressed_in | cell_type | 0.55 |
| benchmark_ot_ad_answer_key:ALX | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PCTR1 | activates | compound | 0.80 |
| rapamycin | targets | drug | 0.60 |
| benchmark_ot_ad_answer_key:ALX | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
pharmacology | 2026-04-11 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||