Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PYRUVATE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| LACTATE | causes | phenotype | 0.65 |
| PI3K/AKT/MTOR | inhibits | pathway | 0.65 |
| PI3K/AKT/MTOR | regulates | pathway | 0.65 |
| NEURON | protects_against | cell_type | 0.65 |
| APP | produces | gene | 0.60 |
| HK2 | inhibits | gene | 0.60 |
| RIBOSOME | associated_with | organelle | 0.45 |
| NEURONS | associated_with | cell_type | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| SIRT1 | interacts_with | gene | 0.65 |
| SIRT1 | modifies | gene | 0.65 |
| LACTATE | produces | phenotype | 0.65 |
| OXIDATIVE PHOSPHORYLATION | activates | phenotype | 0.65 |
| MYC | converts | gene | 0.60 |
| LACTATE | converts | phenotype | 0.60 |
| NEURONS | converts | cell_type | 0.60 |
| LDHA | implicated_in | gene | 0.55 |
| RAPAMYCIN | associated_with | drug | 0.45 |
| MTOR SIGNALING | associated_with | pathway | 0.45 |
| PI3K/AKT/MTOR | associated_with | pathway | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Lactate/Pyruvate Ratio Dynamics in CSF as a Neuroinflammatio | 0.486 | translational neuroscience | Which metabolic biomarkers can distingui |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||