Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about POLYGONATUM SIBIRICUM POLYSACCHARIDE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | POLYGONATUM SIBIRICUM POLYSACCHARIDE |
Knowledge base pages for this entity
graph TD
POLYGONATUM_SIBIRICUM_POLYSACC["POLYGONATUM SIBIRICUM POLYSACCHARIDE"]
POLYGONATUM_SIBIRICUM_POLYSACC -->|"activates"| Pi3K_Akt_Mtor_Signaling_Pathwa["Pi3K/Akt/Mtor Signaling Pathway"]
POLYGONATUM_SIBIRICUM_POLYSACC -->|"activates"| PI3K_Akt_mTOR["PI3K/Akt/mTOR"]
POLYGONATUM_SIBIRICUM_POLYSACC -->|"treats"| Sarcopenia["Sarcopenia"]
POLYGONATUM_SIBIRICUM_POLYSACC -->|"treats"| Mitochondrial_Dysfunction["Mitochondrial Dysfunction"]
POLYGONATUM_SIBIRICUM_POLYSACC -->|"downregulates"| P21["P21"]
POLYGONATUM_SIBIRICUM_POLYSACC -->|"upregulates"| MYOD["MYOD"]
POLYGONATUM_SIBIRICUM_POLYSACC -.protects against.-> Oxidative_Stress["Oxidative Stress"]| Target | Relation | Type | Str |
|---|---|---|---|
| Pi3K/Akt/Mtor Signaling Pathway | activates | pathway | 0.95 |
| PI3K/Akt/mTOR | activates | pathway | 0.90 |
| Skeletal Muscle Mass | associated_with | phenotype | 0.90 |
| Sarcopenia | treats | disease | 0.90 |
| Mitochondrial Dysfunction | treats | phenotype | 0.90 |
| PI3K/Akt/mTOR Signaling Pathway | activates | pathway | 0.85 |
| Mitochondrial Membrane Potential | modulates | phenotype | 0.85 |
| Myoblast Differentiation | associated_with | process | 0.85 |
| CDKN1A | downregulates | gene | 0.85 |
| TP53 | downregulates | gene | 0.85 |
| CDKN2A | downregulates | gene | 0.85 |
| MYOD1 | upregulates | gene | 0.85 |
| MYOGENIN | upregulates | gene | 0.85 |
| C2C12 Cell Viability | promotes | phenotype | 0.85 |
| Myotube Differentiation | promotes | process | 0.85 |
| Mitochondrial Reactive Oxygen Species | suppresses | biomarker | 0.85 |
| Sarcopenia | treats | disease | 0.85 |
| P21 | downregulates | protein | 0.85 |
| MYOD | upregulates | gene | 0.85 |
| Oxidative Stress | protects_against | process | 0.85 |
| Mitochondrial ROS | downregulates | biomarker | 0.80 |
| Mitochondrial Membrane Potential | associated_with | phenotype | 0.80 |
| Muscle Strength | associated_with | phenotype | 0.80 |
| Mitochondrial Dysfunction | treats | disease | 0.80 |
| P21 | downregulates | gene | 0.80 |
| MYOD | upregulates | gene | 0.80 |
| skeletal muscle aging | ameliorates | process | 0.70 |
| mitochondrial dysfunction | ameliorates | process | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||