Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RILPPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Rab Interacting Lysosomal Protein Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
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| Gene Symbol | RILPPROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | </th><td>Lysosomes, Late Endosomes</td></tr> |
| Molecular Weight | 48 kDa |
| Amino Acids | 150 aa |
| GeneCards | RILPPROTEIN |
| Human Protein Atlas | RILPPROTEIN |
| Rab-binding region | Interacts with active GTP-bound Rab7 |
| Dimerization interface | Facilitates RILP homodimer formation |
| Coiled-coil motifs | Mediates protein-protein interactions |
| Dynein-dynactin recruitment site | Binds dynein light intermediate chain |
| Dimerization domain | Stabilizes RILP dimers |
| Regulatory region | Contains phosphorylation sites |
| Associated Diseases | Als |
| Known Drugs/Compounds | rapamycin |
| Interactions | ALZHEIMER'S DISEASE, AMPK, AND, ATG5, ATM, ATP6V1G1 |
| KG Connections | 93 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
RILPPROTEIN["RILPPROTEIN"]
neurodegeneration["neurodegeneration"]
RILPPROTEIN -->|"implicated_in"| neurodegeneration
style RILPPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RILPPROTEIN in their description or question text
No additional research found