Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPL36: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | RPL36 |
| Full Name | RPL36 |
| Protein Type | Gene |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | Cytoplasmic, associated with the 60S ribosomal subunit |
| Molecular Weight | 12.4 kDa |
| Amino Acids | 105 aa |
| Pathways | mtor, mTOR, mTOR signaling |
| NCBI Gene ID | Search NCBI |
| GeneCards | RPL36 |
| Human Protein Atlas | RPL36 |
| Associated Diseases | cell size |
| Interactions | MYC, EP300, CREBBP, TMEM24, CANCER, RPL29 |
| KG Connections | 12 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
RPL36["<b>RPL36</b>"]
Ms{"Ms"}
RPL36 -->|"inhibits"| Ms
Cancer{"Cancer"}
RPL36 -->|"inhibits"| Cancer
MYC["MYC"]
RPL36 -->|"inhibits"| MYC
CANCER["CANCER"]
RPL36 -->|"inhibits"| CANCER
EP300["EP300"]
RPL36 -->|"inhibits"| EP300
CREBBP["CREBBP"]
RPL36 -->|"inhibits"| CREBBP
neurodegeneration["neurodegeneration"]
RPL36 -->|"implicated in"| neurodegeneration
RPL29["RPL29"]
RPL29 -->|"inhibits"| RPL36
style RPL36 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| TMEM24 | binds | protein | 0.80 |
| PI3K-AKT-mTOR | inhibits | pathway | 0.80 |
| cell size | associated_with | phenotype | 0.80 |
| TMEM24 | interacts_with | protein | 0.80 |
| cryptophyte and haptophyte plastids | expressed_in | cell_type | 0.70 |
| Ms | inhibits | disease | 0.65 |
| Cancer | inhibits | disease | 0.65 |
| MYC | inhibits | gene | 0.60 |
| EP300 | inhibits | gene | 0.60 |
| CREBBP | inhibits | gene | 0.60 |
| CANCER | inhibits | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| RPL29 | inhibits | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity