disease

TNBC

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TNBC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections
0Hypotheses
0Analyses
7Outgoing
8Incoming

No summary available yet. View on Wiki →

Disease Info
Associated GenesPRMT1, PHGDH, FASN
Therapeutic AgentsLUTEOLIN, Salidroside
KG Connections15 knowledge graph edges
DatabasesOMIMOrphanetClinicalTrialsPubMed

Wiki Pages (1)

Knowledge base pages for this entity

WDR41 Gene

gene · 1570 words

Pathway Diagram

graph TD
    TNBC["TNBC"] -->|"causes"| Brain_Metastasis["Brain Metastasis"]
    style Brain_Metastasis fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    TNBC["TNBC"] -->|"associated"| Perivascular_Sheath_Formation["Perivascular Sheath Formation"]
    style Perivascular_Sheath_Formation fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    TNBC["TNBC"] -->|"interacts"| Astrocyte["Astrocyte"]
    style Astrocyte fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    TNBC["TNBC"] -->|"interacts"| Microglia["Microglia"]
    style Microglia fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    TNBC["TNBC"] -->|"interacts"| ASTROCYTES["ASTROCYTES"]
    style ASTROCYTES fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Salidroside["Salidroside"] -->|"treats"| TNBC["TNBC"]
    style Salidroside fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Ferroptosis_Related_Genes["Ferroptosis-Related Genes"] -->|"biomarker for"| TNBC["TNBC"]
    style Ferroptosis_Related_Genes fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    WDR41["WDR41"] -->|"regulates"| TNBC["TNBC"]
    style WDR41 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    LUTEOLIN["LUTEOLIN"] -->|"treats"| TNBC["TNBC"]
    style LUTEOLIN fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    MMP9["MMP9"] -->|"activates"| TNBC["TNBC"]
    style MMP9 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    style TNBC fill:#ef5350,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (7)

TargetRelationTypeStr
Brain Metastasiscausesdisease0.95
Brain Metastasisassociated_withdisease0.95
Perivascular Sheath Formationassociated_withphenotype0.90
Perivascular Sheath Formationpromotesphenotype0.90
Astrocyteinteracts_withcell_type0.85

Incoming (8)

SourceRelationTypeStr
Salidrosidetreatscompound0.95
Ferroptosis-Related Genesbiomarker_forbiomarker0.80
WDR41downregulatesprotein0.70
LUTEOLINtreatsdrug0.64
MMP9activatesprotein0.64

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found