FASN

Understanding Entity Pages

This page aggregates everything SciDEX knows about FASN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

FASN is a gene implicated in neurodegeneration research. Key relationships include: activates, inhibits, regulates. Associated with AD, AMI, ARM. Connected to 204 entities in the SciDEX knowledge graph.

View on Wiki →

graph TD
    FASN["FASN<br/>Fatty Acid Synthase"] -->|"activates"| AKT["AKT/PI3K Pathway"]
    FASN -->|"activates"| AMPK["AMPK"]
    FASN -->|"activates"| Glycolysis["Glycolysis"]
    FASN -->|"activates"| HK1["HK1"]
    FASN -->|"activates"| G6PD["G6PD"]

    FASN -->|"inhibits"| Apoptosis["Apoptosis"]
    FASN -->|"inhibits"| BAX["BAX"]
    FASN -->|"inhibits"| Ferroptosis["Ferroptosis"]
    FASN -->|"inhibits"| ACSL4["ACSL4"]
    FASN -->|"inhibits"| Cholesterol["Cholesterol Synthesis"]

    AMPK -->|"activates"| FASN
    ACSL4 -->|"inhibits"| FASN

    FASN -->|"implicated in"| AD["Alzheimer's Disease"]
    FASN -->|"associated with"| Aging["Aging"]
    FASN -->|"activates"| Cancer["Cancer"]

    style FASN fill:#e74c3c,stroke:#c0392b,color:#e0e0e0
    style AKT fill:#3498db,stroke:#2980b9,color:#e0e0e0
    style Ferroptosis fill:#f39c12,stroke:#e67e22,color:#e0e0e0
    style AD fill:#9b59b6,stroke:#8e44ad,color:#e0e0e0
    style Cancer fill:#9b59b6,stroke:#8e44ad,color:#e0e0e0