Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about akt1-protein: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | AKT1 |
| Aliases | akt1-protein |
| Function | Akt1 Protein plays an important role in the study of neurodegenerative diseases |
| Amino Acids | 480 aa |
| GeneCards | AKT1 |
| Human Protein Atlas | AKT1 |
| Associated Diseases | Parkinson, Ms, Ataxia, Cancer, Als, Aging |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
AKT1["AKT1"]
PTEN["PTEN"]
AKT1 -->|"treats"| PTEN
ATG["ATG"]
AKT1 -->|"interacts_with"| ATG
ATF6["ATF6"]
AKT1 -->|"inhibits"| ATF6
TNF["TNF"]
AKT1 -->|"associated_with"| TNF
P53["P53"]
AKT1 -->|"expressed_in"| P53
NLR["NLR"]
AKT1 -->|"interacts_with"| NLR
Fibrosis["Fibrosis"]
AKT1 -->|"treats"| Fibrosis
NLRP3["NLRP3"]
AKT1 -->|"therapeutic_target"| NLRP3
AND["AND"]
AKT1 -->|"therapeutic_target"| AND
CANCER["CANCER"]
AKT1 -->|"associated_with"| CANCER
TLR4["TLR4"]
AKT1 -->|"associated_with"| TLR4
AKT1 -->|"inhibits"| AND
style AKT1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style PTEN fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style ATG fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style ATF6 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style TNF fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style P53 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style NLR fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style Fibrosis fill:#ef5350,stroke:#333,stroke-width:1px,color:#e0e0e0
style NLRP3 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style AND fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style CANCER fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0
style TLR4 fill:#006494,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||