gene

arx

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about arx: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

9Connections
0Hypotheses
0Analyses
7Outgoing
2Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolARX
Full NameAristaless-Related Homeobox
ChromosomeXp21.3
Protein TypeTranscription Factor
FunctionARX plays critical roles in development and function
Amino Acids60 aa
Gene TypeProtein coding
UniProt IDQ9NUJ1
NCBI Gene ID566
Ensembl IDENSG00000031081
OMIM300382
GeneCardsARX
Human Protein AtlasARX
Associated DiseasesAls, neurodegeneration
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: arx — AlphaFold Q9NUJ1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (18)

Knowledge base pages for this entity

Miller-Dieker Syndrome

disease · 3620 words

Neuronal Migration

mechanism · 3104 words

X-Linked Intellectual Disability

disease · 3062 words

Centrosome

mechanism · 2867 words

DLX6 Protein

protein · 1790 words

Pathway Diagram

flowchart TD
    N0["ARX"]
    N1["Als"]
    N0 -->|"associated with"| N1
    N2["Ms"]
    N0 -->|"regulates"| N2
    N3["GENES"]
    N0 -->|"interacts with"| N3
    N4["PER"]
    N0 -->|"associated with"| N4
    N5["Differentiation"]
    N0 -->|"associated with"| N5
    N6["Synaptic Plasticity"]
    N0 -->|"associated with"| N6
    N7["FMR1"]
    N7 -->|"interacts with"| N0
    N8["neurodegeneration"]
    N0 -->|"implicated in"| N8

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 gene
    class N4 gene
    class N5 pathway
    class N6 pathway
    class N7 gene

Outgoing (7)

TargetRelationTypeStr
Alsassociated_withdisease0.65
Msregulatesdisease0.65
GENESinteracts_withgene0.60
PERassociated_withgene0.60
Differentiationassociated_withpathway0.60

Incoming (2)

SourceRelationTypeStr
FMR1interacts_withgene0.60
benchmark_ot_ad_answer_key:ARXdata_indataset_row0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found