Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about compound 1f: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| necroptosis | associated_with | process | 0.95 |
| TNF-α/NF-κB/MAPK signaling pathway | activates | pathway | 0.90 |
| mitochondria-dependent apoptosis | associated_with | process | 0.90 |
| glioblastoma cell proliferation | inhibits | phenotype | 0.90 |
| orthotopic glioblastoma growth | inhibits | phenotype | 0.85 |
| Glioblastoma | treats | disease | 0.85 |
| glioblastoma survival rate | associated_with | phenotype | 0.80 |
| blood-brain barrier | associated_with | brain_region | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||