protein

epas1-protein

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about epas1-protein: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

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🔬 Protein Info

Gene Symbol	EPAS1
Aliases	epas1-protein
Protein Family	bHLH-PAS transcription factor family
Primary Expression	Highest in endothelial cells, neurons, cardiomyocytes, type II pneumocytes
Subcellular Localization	Nucleus and cytoplasm (-regulated by oxygen)
Molecular Weight	118 kDa
UniProt ID	Q9Y5Q3
GeneCards	EPAS1
Human Protein Atlas	EPAS1
Associated Diseases	Als, Obesity, Schizophrenia, Ms, Hypertension, Autism
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: epas1-protein — AlphaFold Q9Y5Q3 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

epas1-protein

protein · 2900 words

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Pathway Diagram

graph TD
    A["Gene expression"] --> B["epas1 protein"]
    B --> C["Protein folding and<br/>quality control"]
    B --> D["Cellular signaling"]
    C --> E["Proteostasis"]
    D --> F["Neurotoxicity"]
    E --> G["Disease outcome"]
    F --> G
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class B protein
    class G disease

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity