concept

MTORC2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MTORC2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

23Connections
0Hypotheses
0Analyses
13Outgoing
8Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameMTORC2
Key Genes/ProteinsMTOR, AKT, PKC, SGK, FLRT2

Wiki Pages (20)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

NTF4 Protein

protein · 5111 words

Autophagy Mechanisms

mechanism · 4866 words

Rapamycin ALS Trial - mTOR Inhibition for Amyotrophic Lateral Sclerosis

clinical · 4511 words

rapamycin-tauopathy

therapeutic · 3805 words

Pathway Diagram

graph TD
    MTORC2["MTORC2"]
    MTORC2 -->|"regulates"| Cell_Death["Cell Death"]
    MTORC2 -->|"regulates"| Mitoxyperilysis["Mitoxyperilysis"]
    MTORC2 -->|"activates"| AKT["AKT"]
    MTORC2 -->|"phosphorylates"| PKC["PKC"]
    MTORC2 -->|"phosphorylates"| SGK["SGK"]
    MTORC2 -->|"mediates"| Cell_Growth["Cell Growth"]
    MTORC2 -->|"mediates"| Cell_Proliferation["Cell Proliferation"]
    MTOR["MTOR"] -->|"component_of"| MTORC2
    GROWTH_FACTOR_RECEPTORS["GROWTH FACTOR RECEPTORS"] -->|"activates"| MTORC2
    G_PROTEIN_COUPLED_RECEPTORS["G-PROTEIN COUPLED RECEPTORS"] -->|"activates"| MTORC2
    Anabolic_Signals["Anabolic Signals"] -->|"activates"| MTORC2
    RPL26["RPL26"] -->|"activates"| MTORC2
    Nutrient_Limitation["Nutrient Limitation"] -->|"modulates"| MTORC2
    GPCR["GPCR"] -->|"activates"| MTORC2

Outgoing (14)

TargetRelationTypeStr
Cell Deathregulatesprocess0.95
Mitoxyperilysisregulatesprocess0.95
AKTphosphorylatesprotein0.90
PKCphosphorylatesprotein0.90
SGKphosphorylatesprotein0.90

Incoming (9)

SourceRelationTypeStr
MTORcomponent_ofgene0.95
GROWTH FACTOR RECEPTORSactivatesreceptor0.85
G-PROTEIN COUPLED RECEPTORSactivatesreceptor0.85
Anabolic Signalsactivatesprocess0.85
FLRT2regulatesgene0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found