Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about neurodevelopment: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| MAPT | essential_for | gene | 0.90 |
| alcohol exposure | modulates | compound | 0.80 |
| ERK/MAPK | regulates | pathway | 0.70 |
| ERK/MAPK pathway | regulates | pathway | 0.70 |
| SYNGAP1 | promoted: Interneuron SYNGAP1 Deficiency Disrupts Cortical Circuit Assembly During Development | gene | 0.58 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Acid-Degradable LNP-Mediated Prenatal CRISPR Intervention fo | 0.465 | neurodegeneration | CRISPR-based therapeutic approaches for |
Scientific analyses that reference this entity
neurodevelopment | 2026-04-15 | 1 hypotheses Top: 0.576
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable S [PMID:34586830] | Picó S, Parras A, Santos-Galindo M, Pose | Sci Transl Med | 2021 | 0 |