process

Gut Microbiota

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Gut Microbiota: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

290Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

No summary available yet. View on Wiki →

🧬 Biological Process Info

Name	Gut Microbiota
Related Diseases	Parkinson's Disease, Motor Deficits, Alzheimer's Disease
Related Pathways	Gut-Brain Axis, DNA Methylation, Histone Modifications

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    Gut_Microbiota["Gut Microbiota"] -->|"associated"| Parkinson_s_Disease["Parkinson's Disease"]
    style Parkinson_s_Disease fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Gut_Microbiota["Gut Microbiota"] -->|"associated"| Indoleacetic_Acid["Indoleacetic Acid"]
    style Indoleacetic_Acid fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Gut_Microbiota["Gut Microbiota"] -->|"modulates"| Central_Nervous_System["Central Nervous System"]
    style Central_Nervous_System fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Gut_Microbiota["Gut Microbiota"] -->|"regulates"| Gut_Brain_Axis["Gut-Brain Axis"]
    style Gut_Brain_Axis fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    Gut_Microbiota["Gut Microbiota"] -->|"regulates"| Central_Nervous_System_Physiol["Central Nervous System Physiology"]
    style Central_Nervous_System_Physiol fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    Gut_Microbiota["Gut Microbiota"] -->|"causes"| Motor_Deficits["Motor Deficits"]
    style Motor_Deficits fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    Gut_Microbiota["Gut Microbiota"] -->|"causes"| Neuroinflammation["Neuroinflammation"]
    style Neuroinflammation fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    Antioxidants["Antioxidants"] -->|"modulates"| Gut_Microbiota["Gut Microbiota"]
    style Antioxidants fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Neural_Pathway["Neural Pathway"] -->|"mediates"| Gut_Microbiota["Gut Microbiota"]
    style Neural_Pathway fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    Fecal_Microbial_Transplantatio["Fecal Microbial Transplantation"] -->|"targets"| Gut_Microbiota["Gut Microbiota"]
    style Fecal_Microbial_Transplantatio fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    Quinic_Acid["Quinic Acid"] -->|"modulates"| Gut_Microbiota["Gut Microbiota"]
    style Quinic_Acid fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Traditional_Chinese_Medicine["Traditional Chinese Medicine"] -->|"modulates"| Gut_Microbiota["Gut Microbiota"]
    style Traditional_Chinese_Medicine fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    style Gut_Microbiota fill:#5d4400,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (110)

Target	Relation	Type	Str
Enteric Nervous System	interacts_with	cell_type	0.95
Parkinson's Disease	associated_with	disease	0.95
Indoleacetic Acid	associated_with	compound	0.95
Central Nervous System	modulates	cell_type	0.95
Gut-Brain Axis	regulates	pathway	0.95
Central Nervous System Physiology	regulates	process	0.95
Motor Deficits	causes	phenotype	0.95
Neuroinflammation	causes	process	0.95
Gut-Brain Axis	component_of	pathway	0.95
Brain Functions	associated_with	process	0.95
Alzheimer's Disease	involved_in	disease	0.95
Host Immunity	regulates	process	0.95
Host Metabolism	regulates	process	0.95
DNA Methylation	modulates	mechanism	0.95
Histone Modifications	modulates	mechanism	0.95
Gut-Microbiome-Brain Axis	mediates	pathway	0.95
RNA Methylation	modulates	mechanism	0.95
Parkinson'S Disease	associated_with	disease	0.95
Alzheimer'S Disease	associated_with	disease	0.95
Parkinson'S Disease	regulates	disease	0.95
Tryptophan Metabolites	associated_with	compound	0.90
Tryptophan Metabolites	product_of	compound	0.90
Indole Derivatives	product_of	compound	0.90
Obesity	associated_with	disease	0.90
Microglia Activation	causes	process	0.90
Mood	modulates	phenotype	0.90
Cognition	modulates	phenotype	0.90
Brain	modulates	cell_type	0.90
Glycerophospholipid Metabolism	regulates	pathway	0.90
N6-Methyladenosine	regulates	compound	0.90
Central Nervous System	associated_with	cell_type	0.90
Disease Pathogenesis	contributes_to	mechanism	0.90
Glaucoma	protects_against	disease	0.90
Immune System	modulates	process	0.88
Metabolite Production	regulates	process	0.88
Neuroinflammation	modulates	process	0.88
Tau-Mediated Neurodegeneration	contributes_to	process	0.88
Central Nervous System Homeostasis	regulates	process	0.87
Central Nervous System	interacts_with	structure	0.85
Systemic Inflammation	modulates	process	0.85
Metabolic Dysfunction	modulates	phenotype	0.85
SNCA Pathology	modulates	process	0.85
Parkinson's Disease	risk_factor_for	disease	0.85
Microglia Activation	modulates	process	0.85
Neuroinflammation	regulates	process	0.85
Glaucoma	associated_with	disease	0.85
Post-Stroke Depression	contributes_to	disease	0.85
PARKINSON'S DISEASE	contributes_to	disease	0.85
ALZHEIMER'S DISEASE	contributes_to	disease	0.85
Neurodevelopment	regulates	process	0.85

Incoming (180)

Source	Relation	Type	Str
IPA	associated_with	compound	0.95
Antioxidants	modulates	compound	0.95
Neural Pathway	mediates	pathway	0.90
AGING	modulates	phenotype	0.90
APOE	interacts_with	gene	0.88
Quinic Acid	modulates	compound	0.85
Fecal Microbial Transplantation	targets	drug	0.85
Postbiotics	modulates	compound	0.85
Akkermansia Muciniphila	modulates	compound	0.80
Fecal Microbial Transplantation	modulates	drug	0.80
Traditional Chinese Medicine	modulates	drug	0.75
Neuroinflammation	regulates	process	0.50
PARKINSON	regulates	gene	0.50
Parkinson's Disease	regulates	disease	0.50
disease	regulates	disease	0.50
PARKINSON'S	regulates	concept	0.50
Microbiota	regulates	process	0.50
microglia	activates	cell_type	0.50
Microbiota	activates	process	0.50
Microbiota	associated_with	process	0.50
AUTISM	associated_with	disease	0.50
SCHIZOPHRENIA	associated_with	disease	0.50
ALZHEIMER	associated_with	gene	0.50
PARKINSON	associated_with	gene	0.50
Alzheimer'S Disease	associated_with	disease	0.50
OBESITY	associated_with	disease	0.50
ANXIETY	associated_with	gene	0.50
disease	associated_with	disease	0.50
ALZHEIMER'S	associated_with	concept	0.50
PARKINSON'S	associated_with	concept	0.50
Neurodegeneration	interacts_with	disease	0.50
Microbiota	interacts_with	process	0.50
Dysbiosis	interacts_with	disease	0.50
PARKINSON	interacts_with	gene	0.50
Parkinson's Disease	interacts_with	disease	0.50
disease	interacts_with	disease	0.50
PARKINSON'S	interacts_with	concept	0.50
inflammation	associated_with	pathway	0.50
Dysbiosis	associated_with	disease	0.50
DEPRESSION	inhibits	disease	0.50
inflammation	inhibits	pathway	0.50
ANXIETY	inhibits	gene	0.50
Microbiota	inhibits	process	0.50
Cognitive Impairment	inhibits	phenotype	0.50
Microbiota	causes	process	0.50
Dysbiosis	causes	disease	0.50
OBESITY	inhibits	disease	0.50
Dysbiosis	inhibits	disease	0.50
Prion	associated_with	protein	0.50
SYNUCLEIN	associated_with	concept	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Gut Microbiota

Understanding Entity Pages

Wiki Pages (20)

Blood-Brain Barrier Dysfunction in Neurodegeneration

Mitophagy Pathway in Neurodegeneration

Neuroprotection Strategies in Neurodegeneration

Mediterranean and MIND Diets for Neurodegeneration

Neuroinflammation-Mitochondria Crosstalk Pathway

Gut-Brain Axis in Neurodegeneration

Psychobiotic Therapy for Neurodegenerative Diseases

Neuroinflammation Across AD, PD, ALS, FTD, and HD

Gut-Microbiome-Neurodegeneration Axis

Advanced Glycation End Products in Neurodegeneration

Neuroinflammation in Parkinson's Disease

Gut Microbiome-Based Therapy for Neurodegeneration

university-of-rochester

Circadian Rhythm Dysfunction in Alzheimer's Disease

thomas-jefferson-university

Urolithin A for Neurodegeneration

TLR5-Mediated Microglial Neuroinflammation Hypothesis

Testosterone Signaling in Neurodegeneration