🧫

Brain-derived extracellular vesicles proteome analysis

active
experiment Created: 2026-04-12T18:03:52 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-2eedd52d-50ac-43fd-9d6b-a
🧫 Experiment Protocol Protein Interactionproposed
Related Entities
P2rx7
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-12T18:03:52.308502'}
p_valueNone
protocolEV isolation, proteomic analysis by mass spectrometry, single-molecule super-resolution microscopy validation
effect_sizeNone
sample_sizeNone
source_pmid40678243
extracted_at2026-04-12T11:03:51.877225
_schema_version1
experiment_typeprotein_interaction
success_criteriaSignificant enrichment of tau and mitochondrial proteins in EVs from P2rx7-expressing mice
expected_outcomesP2RX7 increases tau and mitochondrial protein loading in brain-derived EVs
statistical_methodsProteomic statistical analysis
📊 Evidence Profile
Evidence Balance
+0%
Certainty
45%
Debates
0
Incoming
9
Outgoing
11
0 supporting 0 contradicting 0 neutral
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