🧫

Single-cell RNA sequencing of mouse brains

experiment Created: 2026-04-12 18:03:52 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-e42d5c0e-84d7-4fdc-9e58-1
🧫 Experiment Protocol Gene Expression
🧫 View Full Experiment Page →
Related Entities
P2rx7
Metadata
experiment_typegene_expression
protocolSingle-cell dissociation, RNA sequencing, bioinformatics analysis for cell type identification and differential expression
expected_outcomesP2rx7 expression predominantly in microglia with associated inflammatory changes
success_criteriaClear identification of P2rx7 in microglia and inflammatory gene upregulation
sample_sizeNone
statistical_methodsSingle-cell RNA-seq bioinformatics pipeline
p_valueNone
effect_sizeNone
extracted_at2026-04-12T11:03:51.877223
source_pmid40678243
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-12T18:03:52.169104'}
🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

Linked Artifacts (73)
related🧫P2rx7 genetic deletion in PS19 tauopathy mice100%
related🧫Cell type-specific P2rx7 deletion in microglia vs astrocytes100%
related🧫Brain-derived extracellular vesicles proteome analysis100%
related🧫P2rx7 congenic mouse model insulin tolerance testing100%
related🧫BDEV injection and recipient microglial transcriptome analys100%
related🧫P2rx7 congenic mouse model glucose tolerance testing100%
related🧫P2RX7 variant rs1718119 association with glucose homeostasis100%
mentions📖p2rx780%
mentions📖P2RX7 Protein80%
related📖p2rx772%
related📖P2RX7 Protein72%
mentions📖RNA Binding Fox-1 Homolog 1 (RBFOX1)70%
mentions📖RNA Binding Fox-1 Homolog 2 (RBFOX2)70%
mentions📖RNA Binding Fox-3 Homolog (NeuN) (RBFOX3)70%
mentions📖RNA Therapeutics: Investment Landscape Analysis70%
mentions📖RNA Therapeutics for Neurodegeneration Investment Landscape70%
mentions📖RNA Metabolism Dysfunction in Corticobasal Syndrome70%
mentions📖RNA Metabolism Dysregulation in Alzheimer's Disease70%
mentions📖RNA G-quadruplexes in Neurodegeneration70%
mentions📖RNA Granule Dysfunction in Neurodegeneration70%
mentions📖RNA Metabolism in Neurodegeneration70%
mentions📖RNA Metabolism Dysregulation in 4R-Tauopathies70%
mentions📖RNA Metabolism in Alzheimer's Disease70%
mentions📖RNA Metabolism Dysregulation Pathway70%
mentions📖RNA Processing in Neurodegeneration70%
mentions📖RNA Splicing in Neurodegeneration70%
mentions📖RNA Splicing Dysregulation in 4R-Tauopathies: A Comparative 70%
mentions📖RNA Splicing Defects in Neurodegeneration70%
mentions📖RNA Stability and Decay70%
mentions📖RNA-Targeted Therapies in Neurodegeneration70%
mentions📖RNA-Targeted Therapeutics Investment Synthesis70%
mentions📖RNA Toxicity Pathway70%
mentions📖RNA Editing Therapeutics70%
mentions📖RNA-Based Therapeutics for Alzheimer's Disease70%
mentions📖RNA-Targeting Therapies for Neurodegenerative Diseases70%
mentions📖RNA Targeting Therapy for Neurodegeneration70%
mentions📖RNA-Based Therapeutics for Neurodegenerative Diseases70%
mentions📖RNA Interference (RNAi) Therapies for Neurodegeneration70%
related📖RNA Binding Fox-1 Homolog 1 (RBFOX1)63%
related📖RNA Binding Fox-1 Homolog 2 (RBFOX2)63%
related📖RNA Binding Fox-3 Homolog (NeuN) (RBFOX3)63%
related📖RNA Therapeutics: Investment Landscape Analysis63%
related📖RNA Therapeutics for Neurodegeneration Investment Landscape63%
related📖RNA Metabolism Dysfunction in Corticobasal Syndrome63%
related📖RNA Metabolism Dysregulation in Alzheimer's Disease63%
related📖RNA G-quadruplexes in Neurodegeneration63%
related📖RNA Granule Dysfunction in Neurodegeneration63%
related📖RNA Metabolism in Neurodegeneration63%
related📖RNA Metabolism Dysregulation in 4R-Tauopathies63%
related📖RNA Metabolism in Alzheimer's Disease63%
related📖RNA Metabolism Dysregulation Pathway63%
related📖RNA Processing in Neurodegeneration63%
related📖RNA Splicing in Neurodegeneration63%
related📖RNA Splicing Dysregulation in 4R-Tauopathies: A Comparative 63%
related📖RNA Splicing Defects in Neurodegeneration63%
related📖RNA Stability and Decay63%
related📖RNA-Targeted Therapies in Neurodegeneration63%
related📖RNA-Targeted Therapeutics Investment Synthesis63%
related📖RNA Toxicity Pathway63%
related📖RNA Editing Therapeutics63%
related📖RNA-Based Therapeutics for Alzheimer's Disease63%
related📖RNA-Targeting Therapies for Neurodegenerative Diseases63%
related📖RNA Targeting Therapy for Neurodegeneration63%
related📖RNA-Based Therapeutics for Neurodegenerative Diseases63%
related📖RNA Interference (RNAi) Therapies for Neurodegeneration63%
mentions📖cell-types60%
mentions📖Microglia60%
mentions📖Microglia60%
related📖Alzheimer's Disease60%
related📖Alzheimer's Disease54%
related📖cell-types54%
related📖Microglia54%
related📖Microglia54%