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P2rx7 congenic mouse model insulin tolerance testing

experiment Created: 2026-04-10 14:45:00 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-6494a58a-4859-4890-9f1a-2
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Related Entities
P2rx7
Metadata
experiment_typeanimal_model
protocolinsulin tolerance testing comparing congenic mouse strains
expected_outcomesreduced insulin sensitivity in hypomorphic P2rx7 mice
success_criteriasignificant difference in insulin tolerance between P2x7-C57 and P2x7-129 mice
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T07:45:00.571023
source_pmid25719930
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T14:45:00.657023'}
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

Linked Artifacts (28)
derives_from📄Variation in glucose homeostasis traits associated with P2RX100%
related🧫P2rx7 genetic deletion in PS19 tauopathy mice100%
related🧫Cell type-specific P2rx7 deletion in microglia vs astrocytes100%
related🧫Brain-derived extracellular vesicles proteome analysis100%
related🧫BDEV injection and recipient microglial transcriptome analys100%
related🧫P2rx7 congenic mouse model glucose tolerance testing100%
related🧫Single-cell RNA sequencing of mouse brains100%
related🧫P2RX7 variant rs1718119 association with glucose homeostasis100%
mentions📖p2rx780%
mentions📖P2RX7 Protein80%
related📖p2rx772%
related📖P2RX7 Protein72%
mentions📖p2x7-receptor-neurons70%
mentions📖Purinergic Receptor P2X 7 (P2X7)70%
mentions📖p2x770%
mentions📖P2X7 Protein70%
mentions📖P2X7 Receptor Protein70%
mentions📖P2X7 Receptor Antagonists for Neurodegeneration70%
mentions📖P2X7 Receptor Antagonists for Parkinson's Disease70%
mentions📖P2X7 Receptor Modulation Therapy70%
related📖p2x7-receptor-neurons63%
related📖Purinergic Receptor P2X 7 (P2X7)63%
related📖p2x763%
related📖P2X7 Protein63%
related📖P2X7 Receptor Protein63%
related📖P2X7 Receptor Antagonists for Neurodegeneration63%
related📖P2X7 Receptor Antagonists for Parkinson's Disease63%
related📖P2X7 Receptor Modulation Therapy63%