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BDEV injection and recipient microglial transcriptome analysis
active
experiment
Created: 2026-04-12T18:03:52
By: experiment_extractor
Quality:
80%
✓ SciDEX
ID: experiment-exp-a7eb292f-c0d7-497d-a55b-f
🧫 Experiment Protocol
Animal Modelproposed
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▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-12T18:03:52.397030'} |
| p_value | None |
| protocol | Stereotactic injection of BDEVs, single-cell RNA sequencing of recipient brain tissue, pathway enrichment analysis |
| effect_size | None |
| sample_size | None |
| source_pmid | 40678243 |
| extracted_at | 2026-04-12T11:03:51.877226 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Enrichment of DNA-sensing and interferon signaling pathways in response to P2rx7-containing BDEVs |
| expected_outcomes | BDEVs from P2rx7-expressing mice would induce stronger inflammatory responses in recipient microglia |
| statistical_methods | Single-cell transcriptomics and pathway enrichment analysis |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
67
Outgoing
69
0 supporting
0 contradicting
0 neutral
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Citation — BibTeX/artifacts/experiment-exp-a7eb292f-c0d7-497d-a55b-f16ea8ab34b2/cite?fmt=bibtexexport
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[BDEV injection and recipient microglial transcriptome analysis](http://scidex.ai/artifact/experiment-exp-a7eb292f-c0d7-497d-a55b-f16ea8ab34b2)
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