🧫

α7nAChR agonist treatment rescues HFD-induced memory deficits

active
experiment Created: 2026-04-10T22:50:30 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-d8bfd8d9-639f-433e-9e74-2
🧫 Experiment Protocol Animal Modelproposed
Related Entities
CHRNA7
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:50:30.629431'}
p_valueNone
protocolIntracerebroventricular administration of PNU-282987 for 3 days in HFD-fed mice, followed by behavioral and molecular analysis
effect_sizeNone
sample_sizeNone
source_pmid41565126
extracted_at2026-04-10T15:50:30.524119
_schema_version1
experiment_typeanimal_model
success_criteriaRestoration of memory function and inflammatory markers to control levels
expected_outcomesPNU-282987 treatment would improve memory performance and reduce neuroinflammation in HFD-fed mice
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
85%
Debates
0
Incoming
17
Outgoing
11
0 supporting 0 contradicting 0 neutral
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