| sess_SDA-2026-04-10- | All participants identified BBB penetration as a critical bottleneck, but no exi | 0.50 | 0 | 4 | completed | 2026-04-20 | SDA-2026-04-10-gap-debate-20260410-112625-6c2ceffa |
| sess_SDA-2026-04-19- | Investigate shared DNA methylation age acceleration and histone modification pat | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-19-gap-epigenetic-comparative-ad-pd-als |
| sess_SDA-2026-04-11- | The debate generated therapeutic hypotheses targeting different cell types but n | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-11-gap-debate-20260410-112336-ccdef571 |
| sess_SDA-2026-04-11- | The debate identified that ketone levels >2.0 mM may disrupt astrocyte-neuron me | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-11-gap-debate-20260410-112343-6340ce52 |
| sess_SDA-2026-04-11- | The debate proposed temporal TFEB modulation but identified no validated biomark | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-11-gap-debate-20260410-112348-d9e9b948 |
| sess_SDA-2026-04-11- | The debate highlighted major safety concerns about blocking CXCL10, particularly | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-11-gap-debate-20260410-112406-461e1f01 |
| sess_SDA-2026-04-11- | The debate raised conflicting views on whether myelin restoration would be benef | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-11-gap-debate-20260410-112430-676f2b59 |
| sess_SDA-2026-04-11- | The debate highlighted P2RX7's dual role in both harmful exosome secretion and b | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-11-gap-debate-20260410-112451-1ee4bcc4 |
| sess_SDA-2026-04-11- | The debate highlighted fundamental disagreement about tau's role - whether aggre | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-11-gap-debate-20260410-112457-6c066349 |
| sess_SDA-2026-04-11- | The debate revealed conflicting therapeutic approaches - enhancing DNA repair ve | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-11-gap-debate-20260410-112503-d3625e8c |
| sess_SDA-2026-04-18- | Investigate shared DNA methylation age acceleration and histone modification pat | 1.00 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-18-gap-epigenetic-comparative-ad-pd-als |
| sess_SDA-2026-04-16- | Analyze the spectrum of microglial activation states (DAM, homeostatic, inflamma | 0.50 | 7 | 4 | completed | 2026-04-20 | SDA-2026-04-16-gap-20260416-220243 |
| sess_SDA-2026-04-02- | What are the mechanisms by which tau pathology spreads through connected brain r | 0.50 | 0 | 4 | completed | 2026-04-20 | SDA-2026-04-02-gap-tau-propagation-20260402 |
| wrap_SDA-2026-04-17- | The fundamental premise remains unvalidated despite extensive mechanistic specul | 1.00 | 7 | 4 | completed | 2026-04-19 | SDA-2026-04-17-gap-debate-20260417-033037-c43d12c2 |
| sess_SDA-2026-04-16- | How does lncRNA-0021 achieve sequence-specific binding to mmu-miR-6361 and what | 0.50 | 3 | 4 | completed | 2026-04-18 | |
| sess_SDA-2026-04-11- | The debate proposed P16INK4A-guided targeting but the Skeptic noted microglia ex | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-11-gap-debate-20260410-112619-9c3c13d2 |
| sess_SDA-2026-04-11- | The debate highlighted that long-term CRISPR expression triggers immune response | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-11-gap-debate-20260410-112625-c44578b5 |
| sess_SDA-2026-04-11- | The debate highlighted that TREM2 therapeutic targeting remains contested across | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-11-gap-debate-20260410-112636-141592ba |
| sess_SDA-2026-04-11- | The debate transcript shows incomplete analysis where the Theorist reached maxim | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-11-gap-debate-20260410-112649-f72c1ba2 |
| sess_SDA-2026-04-11- | The debate aimed to cross-reference Allen Aging Mouse Brain Atlas data with huma | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-11-gap-debate-20260410-112700-e284319e |
| sess_SDA-2026-04-11- | The debate was initiated to analyze cell-type-specific vulnerability using SEA-A | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-11-gap-debate-20260410-112706-7f5a9480 |
| sess_SDA-2026-04-11- | The debate initiated investigation into white matter aging and myelin changes bu | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-11-gap-debate-20260410-112718-0b78e493 |
| sess_SDA-2026-04-11- | The debate failed to produce any actual hypotheses despite this being the core r | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-11-gap-debate-20260410-112725-4369698d |
| sess_SDA-2026-04-12- | The debate was structured to identify aging-neurodegeneration mechanisms using A | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-12-gap-debate-20260410-112741-51d89235 |
| sess_SDA-2026-04-12- | The debate transcript shows incomplete information exchange, suggesting this fun | 0.49 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-12-gap-debate-20260410-112747-72269a36 |
| sess_SDA-2026-04-12- | The debate highlighted the bidirectional relationship between sleep and neurodeg | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-12-gap-debate-20260410-112754-fc3e63c8 |
| sess_SDA-2026-04-12- | The theorist proposed this novel approach to enable safe agonism across disease | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-12-gap-debate-20260410-112812-429571d2 |
| sess_SDA-2026-04-12- | The debate revealed that no high-resolution structure exists for the critical hi | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-12-gap-debate-20260410-112837-d8c6fc48 |
| sess_SDA-2026-04-12- | The debate proposed bioenergetic gradients drive transfer but didn't identify th | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-12-gap-debate-20260410-112842-e2dec0d7 |
| sess_SDA-2026-04-16- | How does synaptic protein turnover change with age and neurodegeneration, and wh | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-16-frontier-proteomics-1c3dba72 |
| sess_SDA-2026-04-16- | What are the key metabolic alterations detectable in brain tissue, CSF, and bloo | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-16-frontier-metabolomics-f03b09d9 |
| sess_SDA-2026-04-16- | How does lipid metabolism dysregulation contribute to amyloidogenesis and tau pa | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-16-frontier-lipidomics-dcdbc360 |
| sess_SDA-2026-04-16- | How does chronic peripheral inflammation interact with CNS neuroimmune pathways | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-16-frontier-immunomics-e6f97b29 |
| sess_SDA-2026-04-16- | How does the human brain connectome reorganize in Alzheimer's disease, and what | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-16-frontier-connectomics-84acb35a |
| sess_SDA-2026-04-16- | There's a clear disconnect between improved mechanistic understanding of AD and | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-16-gap-pubmed-20260410-145418-c1527e7b |
| sess_SDA-2026-04-16- | What are the shared DNA methylation age acceleration and histone modification pa | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-16-gap-epigenetic-adpdals |
| sess_SDA-2026-04-16- | While RGS6 deficiency causes Parkinson's-like pathology, whether enhancing RGS6 | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-16-gap-pubmed-20260410-145520-5692b02e |
| sess_SDA-2026-04-17- | Analyze the spectrum of microglial activation states (DAM, homeostatic, inflamma | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-17-gap-20260416-220243 |
| sess_SDA-2026-04-17- | Analyze the spectrum of microglial activation states (DAM, homeostatic, inflamma | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-17-gap-microglial-subtypes-pharmaco-202604170000 |
| sess_SDA-2026-04-17- | While RGS6 deficiency causes Parkinson's-like pathology, whether enhancing RGS6 | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-2026-04-17-gap-pubmed-20260410-145520-5692b02e |
| sess_SDA-2026-04-17- | The fundamental premise remains unvalidated despite extensive mechanistic specul | 0.50 | 7 | 4 | completed | 2026-04-18 | SDA-2026-04-17-gap-debate-20260417-033037-c43d12c2 |
| sess_SDA-NEUROINFLAM | What is the optimal blood-based biomarker panel combining established markers (G | 0.50 | 0 | 4 | completed | 2026-04-18 | SDA-NEUROINFLAM-BIOMARKERPANEL-0b9129bc |
| sess_SDA-2026-04-18- | The debate highlighted compelling correlative evidence for ferroptosis markers i | 0.50 | 4 | 4 | completed | 2026-04-18 | SDA-2026-04-18-gap-debate-20260417-032952-48bdcbea |
| sess_SDA-2026-04-16- | The debate framework mentioned multiple microglial subtypes but no analysis was | 1.00 | 3 | 4 | completed | 2026-04-18 | SDA-2026-04-16-gap-debate-20260410-112642-fffdca96 |
| ds-SDA-2026-04-16-ga | Ferroptosis in ALS and motor neuron disease: GPX4, lipid peroxidation, and iron | 0.59 | 7 | 5 | completed | 2026-04-16 | SDA-2026-04-16-gap-ferroptosis-als-d2fb6bf796ed |
| DEBATE-BIOMNI-125926 | Is the gut microbiome a driver of PD pathology via SCFA depletion, or is dysbios | 0.70 | 2 | 4 | completed | 2026-04-16 | SDA-BIOMNI-MICROBIO-337ee37a |
| DEBATE-BIOMNI-25ad6c | Does the hybrid DAM + interferon-response microglial population represent a nove | 0.70 | 2 | 4 | completed | 2026-04-16 | SDA-BIOMNI-SCRNA_AN-248caecc |
| DEBATE-BIOMNI-f7eed7 | Is REST the master regulator of neuronal vulnerability in AD, or is it one of se | 0.70 | 2 | 4 | completed | 2026-04-16 | SDA-BIOMNI-GENE_REG-785b71fe |
| DEBATE-BIOMNI-46c249 | Does fine-mapping to median 3-variant credible sets provide sufficient resolutio | 0.70 | 2 | 4 | completed | 2026-04-16 | SDA-BIOMNI-FINE_MAP-215bc2c6 |
| DEBATE-BIOMNI-9892a9 | Does the BIN1 non-coding variant mechanism provide a druggable target, or is tra | 0.70 | 2 | 4 | completed | 2026-04-16 | SDA-BIOMNI-VARIANT_-b5b8e32f |