| sess_SDA-2026-04-14- | The authors evaluate several ALS-associated mutations in OPTN's leucine-zipper d | 0.95 | 7 | 4 | completed | 2026-04-16 | SDA-2026-04-14-gap-pubmed-20260410-183548-043c7918 |
| sess_SDA-2026-04-14- | The abstract describes a counterintuitive finding where loss-of-function P/Q mut | 0.95 | 7 | 4 | completed | 2026-04-16 | SDA-2026-04-14-gap-pubmed-20260410-181156-feec7bd3 |
| sess_SDA-2026-04-15- | The abstract claims C. butyricum-GLP-1 crosses the BBB and binds to GLP-1 recept | 0.95 | 7 | 4 | completed | 2026-04-16 | SDA-2026-04-15-gap-pubmed-20260411-093924-7330920b |
| sess_SDA-2026-04-15- | The study shows deferiprone rescues wild-type cells but exacerbates toxicity in | 0.95 | 7 | 4 | completed | 2026-04-16 | SDA-2026-04-15-gap-pubmed-20260411-092119-691e1977 |
| sess_SDA-2026-04-15- | The abstract reveals an unexpected contradiction where PRKN activation, normally | 0.91 | 7 | 4 | completed | 2026-04-16 | SDA-2026-04-15-gap-pubmed-20260411-082509-118fcb37 |
| sess_SDA-2026-04-15- | The abstract shows that acute neuroinflammation becomes persistent with a specif | 0.83 | 7 | 4 | completed | 2026-04-16 | SDA-2026-04-15-gap-pubmed-20260411-075425-2feffb0c |
| sess_SDA-2026-04-15- | The abstract challenges the rationale for using microtubule-stabilizing drugs in | 0.68 | 0 | 4 | completed | 2026-04-16 | SDA-2026-04-15-gap-pubmed-20260410-100455-ff18091d |
| sess_SDA-2026-04-15- | The debate highlighted tau prion-like transmission but did not resolve how diffe | 0.57 | 0 | 4 | completed | 2026-04-16 | SDA-2026-04-15-gap-debate-20260410-112730-24052bbe |
| sess_SDA-2026-04-15- | While TREM2 was identified as critical for microglial senescence, the debate lac | 0.73 | 4 | 4 | completed | 2026-04-16 | SDA-2026-04-15-gap-debate-20260410-112522-57d1cc4f |
| sess_SDA-2026-04-14- | The abstract shows TYROBP deficiency is neuroprotective despite being required f | 0.56 | 0 | 4 | completed | 2026-04-16 | SDA-2026-04-14-gap-pubmed-20260411-072446-a32fa49c |
| sess_SDA-2026-04-14- | The study demonstrates that exercise-conditioned plasma transfers cognitive bene | 0.95 | 7 | 4 | completed | 2026-04-16 | SDA-2026-04-14-gap-pubmed-20260410-191046-15921012 |
| sess_SDA-2026-04-14- | The abstract describes astrocyte phenotypic heterogeneity (A1/A2) but doesn't ex | 0.66 | 0 | 4 | completed | 2026-04-16 | SDA-2026-04-14-gap-pubmed-20260410-183021-c13d9f04 |
| sess_SDA-2026-04-02- | | 0.95 | 7 | 4 | completed | 2026-04-16 | SDA-2026-04-02-gap-v2-e1e1b7c3 |
| sess_SDA-2026-04-14- | The study shows dramatic functional recovery and muscle re-innervation after cyt | 0.85 | 7 | 4 | completed | 2026-04-16 | SDA-2026-04-14-gap-pubmed-20260410-181356-57d1f917 |
| sess_SDA-2026-04-14- | The abstract shows V1613M variant reduces amyloid plaques and damage in 5xFAD mi | 0.60 | 0 | 4 | completed | 2026-04-16 | SDA-2026-04-14-gap-pubmed-20260410-180532-e8930cb8 |
| sess_SDA-2026-04-14- | The finding that Mertk/Axl deficiency increases viral susceptibility contradicts | 0.75 | 0 | 4 | completed | 2026-04-16 | SDA-2026-04-14-gap-pubmed-20260410-174607-708e8d91 |
| sess_SDA-2026-04-15- | The debate identified a critical therapeutic window when astrocytic ketone produ | 0.85 | 3 | 4 | completed | 2026-04-15 | SDA-2026-04-15-gap-debate-20260410-112330-9abf86eb |
| sess_SDA-2026-04-15- | What molecular mechanisms mediate SPP1-induced microglial phagocytic activation | 0.95 | 7 | 5 | completed | 2026-04-15 | SDA-2026-04-15-gap-pubmed-20260406-062118-e3613755 |
| sess_SDA-2026-04-13- | The authors explicitly state that the effects of these novel genes (MATR3, CHCHD | 0.71 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-165527-8256a071 |
| sess_SDA-2026-04-13- | The debate proposed K280 acetylation creates a β-sheet nucleation interface but | 0.86 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-debate-20260412-094556-86f36bb3 |
| sess_SDA-2026-04-13- | The debate proposed K280 acetylation creates a β-sheet nucleation interface but | 0.74 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-debate-20260412-094556-86f36bb3 |
| sess_SDA-2026-04-13- | The debate outlined peripheral immune involvement but failed to address the prec | 0.78 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-debate-20260411-064946-4940f331 |
| sess_SDA-2026-04-13- | The debate outlined peripheral immune involvement but failed to address the prec | 0.67 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-debate-20260411-064946-4940f331 |
| sess_SDA-2026-04-13- | The abstract reports extraordinary dopamine increases (>500-fold in drug-free pa | 0.67 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-145531-5c4e7b59 |
| sess_SDA-2026-04-13- | The study shows homozygous R136S fully rescues APOE4-driven pathology while hete | 0.81 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-145358-185db2c8 |
| sess_SDA-2026-04-13- | The abstract shows microglia ameliorate OxPC toxicity to neurons and oligodendro | 0.68 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-165345-41805e1b |
| sess_SDA-2026-04-13- | The abstract shows microglia ameliorate OxPC toxicity to neurons and oligodendro | 0.62 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-165345-41805e1b |
| sess_SDA-2026-04-13- | The abstract shows microglia ameliorate OxPC toxicity to neurons and oligodendro | 0.92 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-165345-41805e1b |
| sess_SDA-2026-04-13- | Despite FDA warnings and a 315% increased erythrocytosis risk with TRT, the asso | 0.83 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-155308-2c6815fb |
| sess_SDA-2026-04-13- | The study shows that MCT1 disruption leads to axon degeneration and neuron death | 0.78 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-170325-196c7ee5 |
| sess_SDA-2026-04-13- | The study shows that MCT1 disruption leads to axon degeneration and neuron death | 0.82 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-170325-196c7ee5 |
| sess_SDA-2026-04-13- | The study shows VCP-mutant astrocytes exhibit hypoxia response activation withou | 0.78 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-170057-1bea7d88 |
| sess_SDA-2026-04-13- | This study identifies oligodendrocytes as drivers of neuroinflammation in PD, co | 0.79 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-150500-e110aab9 |
| sess_SDA-2026-04-13- | The title suggests B cells actively maintain tolerance to AQP4, but the specific | 0.66 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-142329-c1db787b |
| sess_SDA-2026-04-13- | How does PIKFYVE inhibition activate unconventional protein clearance via exocyt | 0.63 | 0 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-143119-8ae42941 |
| sess_SDA-2026-04-13- | The title suggests B cells actively maintain tolerance to AQP4, but the specific | 0.79 | 3 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-142329-c1db787b |
| sess_SDA-2026-04-13- | While the study shows HDAC1/2 deletion improves amyloid clearance and cognition, | 0.95 | 7 | 4 | completed | 2026-04-14 | SDA-2026-04-13-gap-pubmed-20260410-110327-26e1d6c7 |
| sess_SDA-2026-04-13- | The debate highlighted promising PTMs like K280 acetylation and O-GlcNAcylation | 0.65 | 0 | 4 | completed | 2026-04-13 | SDA-2026-04-13-gap-debate-20260412-094612-a2e3bd09 |
| sess_SDA-2026-04-13- | RNA binding protein dysregulation across ALS FTD AD | 0.50 | 0 | 4 | completed | 2026-04-13 | SDA-2026-04-13-gap-20260410-172514 |
| sess_SDA-2026-04-12- | The debate highlighted BBB penetration as a major hurdle for SPM therapeutics bu | 0.66 | 0 | 4 | completed | 2026-04-13 | SDA-2026-04-12-gap-debate-20260410-113110-2059f65f |
| sess_SDA-2026-04-04- | The provided transcript contains only speaker labels [Theorist] and [Synthesizer | 0.95 | 7 | 4 | completed | 2026-04-13 | SDA-2026-04-04-gap-debate-20260403-222510-20260402 |
| sess_SDA-2026-04-12- | The debate highlighted a critical dosing paradox where both hypo- and hypermethy | 0.82 | 3 | 4 | completed | 2026-04-13 | SDA-2026-04-12-gap-debate-20260410-113051-5dce7651 |
| sess_SDA-2026-04-12- | The debate revealed conflicting evidence about whether connexin-43 mediates mito | 0.74 | 3 | 4 | completed | 2026-04-13 | SDA-2026-04-12-gap-debate-20260410-113038-57244485 |
| sess_SDA-2026-04-12- | The abstract suggests that Aβ-tau synergy could explain negative results from an | 0.70 | 3 | 4 | completed | 2026-04-13 | SDA-2026-04-12-gap-pubmed-20260410-180503-a7a03974 |
| sess_SDA-2026-04-12- | The abstract explicitly questions whether AD's hallmark pathologies induce choli | 0.79 | 3 | 4 | completed | 2026-04-13 | SDA-2026-04-12-20260411-082446-2c1c9e2d |
| sess_SDA-2026-04-12- | The debate identified a critical mechanistic gap between SCFA production by gut | 0.70 | 3 | 4 | completed | 2026-04-13 | SDA-2026-04-12-gap-debate-20260410-113021-6fbc6da4 |
| sess_SDA-2026-04-04- | How do neurodegeneration gene expression patterns in SEA-AD differ from other po | 0.70 | 3 | 4 | completed | 2026-04-13 | SDA-2026-04-04-SDA-2026-04-04-gap-debate-20260403-222549-202 |
| sess_SDA-2026-04-12- | How does APOE4's beneficial immune function reconcile with its established role | 0.78 | 3 | 4 | completed | 2026-04-13 | SDA-2026-04-12-gap-pubmed-20260410-184126-b2c3e2e8 |
| sess_SDA-2026-04-04- | Which metabolic biomarkers can distinguish therapeutic response from disease pro | 0.77 | 3 | 4 | completed | 2026-04-13 | SDA-2026-04-04-SDA-2026-04-04-gap-debate-20260403-222618-c69 |
| sess_SDA-2026-04-12- | Why have numerous phase 3 clinical trials failed despite advances in understandi | 0.67 | 3 | 5 | completed | 2026-04-12 | SDA-2026-04-12-gap-debate-20260410-145418-c1527e7b |