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LAMP2B

LAMP2B

Score: 0.405 Price: $0.38 Low Druggability Status: active
HYPOTHESES
1
PAPERS
7
KG EDGES
0
DEBATES
0

3D Protein Structure

🔮 LAMP2B — AlphaFold P13473 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Druggability & Clinical Context

Druggability
Low
Score: 0.40
Clinical Stage
Phase I
Target Class
Signaling Protein
Safety
0.30
Druggability Analysis
Drug Development0.00
Structural Tractability0.30
Target Class0.50
Safety Profile0.30
Key Metrics
PDB Structures:
0
Known Drugs:
0
Approved:
0
In Clinical Trials:
0
Therapeutic Areas:
neurodegeneration
Mechanism: Prioritized from 1 SciDEX hypotheses, including: Microglia-Derived Extracellular Vesicle Engineering for Targeted Mitochondrial Delivery
Known Drugs:
No known drugs targeting this protein
Structural Data:

🔮 Predicted Protein Structure (AlphaFold)

🔮 LAMP2B — AlphaFold P13473 Click to expand interactive 3D viewer

AI-predicted structure from AlphaFold EBI | Powered by Mol* | Rotate: click+drag | Zoom: scroll

Linked Hypotheses (0)

No linked hypotheses

Linked Experiments (0)

No linked experiments

Scoring Dimensions

Portfolio 0.00 (25%) Druggability 0.40 (20%) Evidence 0.59 (20%) Safety 0.30 (15%) Competitive 0.60 (10%) Connectivity 0.00 (10%) 0.405 composite

Knowledge Graph (20)

associated with (8)

LAMP2B → neurodegeneration
LAMP2B → RAB27A
LAMP2B → LAMP2
LAMP2B → LAMP2A
LAMP2B → TARDBP
...and 3 more

co discussed (2)

LAMP2B → Synthetic fusion proteins
LAMP2B → GJA1

expressed in (3)

LAMP2B → neurons
LAMP2B → RAB27A
LAMP2B → microglia

implicated in (2)

LAMP2B → ms
LAMP2B → als

interacts with (2)

LAMP2B → RAB27A
LAMP2B → NMDAR

participates in (2)

LAMP2B → neurotrophin signaling
LAMP2B → autophagy pathway

regulates (1)

LAMP2B → NMDA

Debate History (0)

No debates yet

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