| Gene Symbol | ADCY3 |
| Full Name | Adenylate cyclase 3 |
| Aliases | ADCY3PROTEIN |
| Chromosome | 2p23.3 |
| Protein Type | Enzyme |
| Function | is a member of the adenylate cyclase family of enzymes that catalyze the conversion of ATP to cyclic AMP (cAMP), a ubiquitous second messenger critical for cellular signaling. |
| Primary Expression | olfactory sensory neurons where it plays a critical role in odor detection and signal transduction |
| Molecular Weight | 140 kDa |
| Amino Acids | 244 aa |
| UniProt ID | [O60236](https://www.uniprot.org/uniprot/O60236) |
| Ensembl ID | ENSG00000138031 |
| OMIM | 600019 |
| GeneCards | ADCY3 |
| Human Protein Atlas | ADCY3 |
| ADCY1, ADCY5, ADCY6, ADCY8, ADCY9 | Other adenylate cyclase isoforms with distinct tissue distributions and regulatory properties |
| Associated Diseases | obesity, Alzheimer's Disease |
| Interactions | GDNF, GFRAL, HDAC6, HEDGEHOG, SHH |
| KG Connections | 16 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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