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hypothesis 2,427 words
Contents

Alzheimer's disease pathology originates in the hippocampus and subsequently spreads

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Knowledge Graph (8 edges)

LRP1-Dependent Tau Uptake Disruption therapeutic_target Alzheimer's Disease
TREM2-mediated microglial tau clearance enhancemen therapeutic_target Alzheimer's Disease
Extracellular Vesicle Biogenesis Modulation therapeutic_target Alzheimer's Disease
VCP-Mediated Autophagy Enhancement therapeutic_target Alzheimer's Disease
HSP90-Tau Disaggregation Complex Enhancement therapeutic_target Alzheimer's Disease
Synaptic Vesicle Tau Capture Inhibition therapeutic_target Alzheimer's Disease
Trans-Synaptic Adhesion Molecule Modulation therapeutic_target Alzheimer's Disease
Tau-Independent Microtubule Stabilization via MAP6 therapeutic_target Alzheimer's Disease

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