biomarker 1,496 words KG: CSF 2026-03-24
kind:biomarkersection:biomarkersstate:published
Contents

14-3-3 Proteins (CSF) - Biomarker

🔬 Protein Info
Gene SymbolCSF
Sporadic CJDTypically Positive
Variant CJDUsually Positive
Familial CJDUsually Positive
FFIVariable
Alzheimer's DiseaseUsually Negative
Associated DiseasesMULTIPLE SCLEROSIS
Known Drugs/CompoundsADUCANUMAB
KG Connections122 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (9)

SASP-Driven Aquaporin-4 Dysregulation
Score: 0.59
Retinal Vascular Microcirculation Rescue
Score: 0.54
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
Noradrenergic-Tau Propagation Blockade
Score: 0.51
Aquaporin-4 Polarization Rescue
Score: 0.51

Related Analyses (5)

Extracellular vesicle biomarkers for early AD detection
neurodegeneration · completed
Neuroinflammation and microglial priming in early Alzheimer'
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs
clinical · proposed · Score: 0.90
CSF Dynamic Biomarkers for Differential Diagnosis of NPH vs
clinical · proposed · Score: 0.40
NPH Glymphatic System Interaction Experiment
clinical · proposed · Score: 0.40

See Also (4)

Tau Consortium
organization · KG edge: expressed_in
Proteome Atlas for Neurodegenerative Diseases
mechanism · KG edge: contains
AQP4 (Aquaporin-4 Gene)
gene · KG edge: loss_affects
Neurodegeneration
disease · KG edge: regulates

Knowledge Graph (12 edges)

CSF contains PROTEOME
CSF contains PD_ProS
CSF activates AQP4
CSF inhibits MELANOMA
CSF associated_with TAU
CSF regulates TAU
CSF interacts_with SYK
CSF activates SYK
CSF stabilizes TAU
CSF produces TAU