protein 1,510 words KG: CASPASE3 2026-03-23
kind:proteinsection:proteinsstate:published
Contents

Caspase-3 (CASP3)

🔬 Protein Info
Gene SymbolCASP3
Full NameCaspase-3 (CASP3)
AliasesCASPASE3
Chromosome4q35.1.
Protein FamilyCysteine-aspartate protease (caspase) family
Protein TypeProtein
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionCytoplasm, mitochondria (activated)
Subcellular LocalizationCytoplasm, mitochondria (activated)
Molecular Weight32 kDa (zymogen); 17 + 12 kDa (active heterodimer)
PathwaysApoptosis
UniProt IDP42574
GeneCardsCASP3
Human Protein AtlasCASP3
GeneCASP3
Associated DiseasesLymphoma
InteractionsJUN, HSP90AA1, AKT1, FOXO1, PIK3CG, PI3K
KG Connections220 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

CASPASE3 associated_with EHMT2
CASPASE3 associated_with BAX
CASPASE3 inhibits JUN
CASPASE3 associated_with CASPASE8
CASPASE3 associated_with BCL2
CASPASE3 associated_with FOXO1
CASPASE3 activates HSP90AA1
CASPASE3 activates AKT1
CASPASE3 activates FOXO1
CASPASE3 activates PIK3CG

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