disease

Lymphoma

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Lymphoma: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

835Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

Summary

Lymphoma is a disease characterized by neurodegeneration research. Key relationships include: activates, associated with, therapeutic target. Associated with Aging, Als, Alzheimer. Connected to 509 entities in the SciDEX knowledge graph.

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Disease Info

Associated Genes	BAX, EHMT2, FOXO1, BCL2, MYC, ALOX12, VEGF, FIS1
KG Connections	736 knowledge graph edges
Databases	OMIM Orphanet ClinicalTrials PubMed

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    Lymphoma["Lymphoma"] -->|"activates"| Ferroptosis["Ferroptosis"]
    Lymphoma["Lymphoma"] -.->|"inhibits"| Apoptosis["Apoptosis"]
    Lymphoma["Lymphoma"] -->|"regulates"| Ferroptosis_1["Ferroptosis"]
    Lymphoma["Lymphoma"] -->|"associated"| Autophagy["Autophagy"]
    Lymphoma["Lymphoma"] -->|"associated"| Akt["Akt"]
    Lymphoma["Lymphoma"] -->|"associated"| Oxidative_Stress["Oxidative Stress"]
    TFR1["TFR1"] -->|"biomarker for"| Lymphoma["Lymphoma"]
    BAX["BAX"] -->|"associated"| Lymphoma["Lymphoma"]
    EHMT2["EHMT2"] -->|"associated"| Lymphoma["Lymphoma"]
    JUN["JUN"] -.->|"inhibits"| Lymphoma["Lymphoma"]
    style Lymphoma fill:#ef5350,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (201)

Target	Relation	Type	Str
Apoptosis	inhibits	pathway	1.00
Apoptosis	activates	pathway	1.00
Apoptosis	therapeutic_target	pathway	1.00
Apoptosis	regulates	pathway	1.00
Inflammation	activates	disease	0.85
Autophagy	associated_with	pathway	0.80
Mtor	therapeutic_target	pathway	0.80
Pi3K/Akt	therapeutic_target	pathway	0.80
Lung Cancer	associated_with	disease	0.75
Ferroptosis	activates	pathway	0.70
Apoptosis	associated_with	pathway	0.70
Immune Response	activates	pathway	0.70
Mapk	therapeutic_target	pathway	0.70
Autophagy	inhibits	pathway	0.70
Nf-Κb	activates	pathway	0.70
Autophagy	activates	pathway	0.70
Angiogenesis	therapeutic_target	pathway	0.70
Mtor	activates	pathway	0.70
Drug Resistance	therapeutic_target	pathway	0.70
Lung Cancer	therapeutic_target	disease	0.65
Autoimmune	activates	disease	0.65
Ferroptosis	regulates	pathway	0.60
Akt	associated_with	pathway	0.60
Oxidative Stress	associated_with	pathway	0.60
Pi3K	associated_with	pathway	0.60
Toll-Like Receptor	associated_with	pathway	0.60
Blood-Brain Barrier	associated_with	pathway	0.60
Mtor	associated_with	pathway	0.60
Epigenetic	activates	pathway	0.60
Sphingolipid	contributes_to	pathway	0.60
Pi3K	therapeutic_target	pathway	0.60
Pi3K	inhibits	pathway	0.60
Akt	therapeutic_target	pathway	0.60
Ubiquitin-Proteasome	therapeutic_target	pathway	0.60
Proteasome	therapeutic_target	pathway	0.60
Mtor	treats	pathway	0.60
Differentiation	therapeutic_target	pathway	0.60
Ras/Raf/Mek	therapeutic_target	pathway	0.60
Immunotherapy	treats	pathway	0.60
Drug Resistance	inhibits	pathway	0.60
Complement	interacts_with	pathway	0.60
Oxidative Stress	activates	pathway	0.60
Toll-Like Receptor	activates	pathway	0.60
Immunotherapy	regulates	pathway	0.60
Car-T	associated_with	pathway	0.60
Erk Signaling	activates	pathway	0.60
Cell Cycle	therapeutic_target	pathway	0.60
Nf-Κb	expressed_in	pathway	0.60
Senescence	expressed_in	pathway	0.60
Immune Response	implicated_in	pathway	0.60

Incoming (634)

Source	Relation	Type	Str
Cancer	associated_with	disease	1.00
BAX	regulates	gene	1.00
AKT	therapeutic_target	gene	1.00
BCL-2	regulates	gene	1.00
APOPTOSIS	activates	gene	1.00
CANCER	therapeutic_target	gene	1.00
APOPTOSIS	therapeutic_target	gene	1.00
BCL-2	therapeutic_target	gene	1.00
APOPTOSIS	inhibits	gene	1.00
APOPTOSIS	regulates	gene	1.00
CANCER	inhibits	gene	1.00
CANCER	regulates	gene	1.00
CANCER	associated_with	gene	1.00
BCL2	activates	gene	1.00
Tumor	therapeutic_target	disease	1.00
Cancer	therapeutic_target	disease	1.00
Als	therapeutic_target	disease	1.00
Cancer	regulates	disease	1.00
Als	activates	disease	1.00
BCL2	associated_with	gene	0.95
MYC	associated_with	gene	0.95
STAT3	activates	gene	0.95
Als	associated_with	disease	0.95
PI3K	therapeutic_target	gene	0.95
GENES	therapeutic_target	gene	0.95
EGFR	inhibits	gene	0.95
INFLAMMATION	activates	gene	0.95
Cancer	inhibits	disease	0.95
Tumor	associated_with	disease	0.85
DNA	regulates	gene	0.85
P53	inhibits	gene	0.85
BCL2	inhibits	gene	0.85
MTOR	therapeutic_target	gene	0.85
MTOR	activates	gene	0.85
AKT	activates	gene	0.85
NRF2	activates	gene	0.85
MYC	activates	gene	0.85
HO-1	activates	gene	0.85
Tumor	inhibits	disease	0.85
EGFR MUTATIONS	inhibits	gene	0.85
Carcinoma	inhibits	disease	0.85
NUCLEAR JAK	contributes_to	protein	0.85
BAX	associated_with	gene	0.75
BCL-2	associated_with	gene	0.75
P53	regulates	gene	0.75
BCL-2	activates	gene	0.75
GENES	inhibits	gene	0.75
BAX	therapeutic_target	gene	0.75
BCL-2	inhibits	gene	0.75
PI3K	inhibits	gene	0.75

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Lymphoma

Understanding Entity Pages

Summary

Wiki Pages (20)

GSK-3β in Neurodegeneration

rankings

DDX3X Gene

RASGRP1 Gene

EPHA7 Gene

Litronesib (LY317615/Enzastaurin)

epigenetics-neurodegeneration

Paraneoplastic Cerebellar Degeneration Neurons

ataxia-telangiectasia

Cerebellar Degeneration Pathway

Kyowa Kirin Co., Ltd.

Cyclophosphamide

MEF2B (Myocyte Enhancer Factor 2B)

CD2AP Gene — CD2-Associated Protein

frontotemporal-lobar-degeneration

Section 187: Advanced Cytokine and Chemokine Network Therapy in CBS/PSP

stiff-person-syndrome

biocon