| Gene Symbol | HSP90AA1 |
| Full Name | Heat Shock Protein 90 Alpha Family Class A Member 1 |
| Chromosome | 14q32.31 |
| Protein Type | Chaperone |
| Target Class | Chaperone |
| Function | Small molecule inhibitor binding to ATP-binding pocket of chaperone |
| Mechanism of Action | Small molecule inhibitor binding to ATP-binding pocket of chaperone |
| Druggability | Low (0.45) |
| Clinical Stage | Phase III |
| Molecular Weight | ~90 kDa |
| Amino Acids | 854 aa |
| Exons | 11 |
| Pathways | NF-κB |
| UniProt ID | P07900 |
| NCBI Gene ID | 3320 |
| Ensembl ID | ENSG00000100425 |
| OMIM | 140571 |
| GeneCards | HSP90AA1 |
| Human Protein Atlas | HSP90AA1 |
| Associated Diseases | ALS, Aging, Alzheimer, Alzheimer'S Disease |
| Known Drugs/Compounds | Chrysotoxine, Atbc, 17-Dmag, Nvp-Auy922, Nvp-Hsp990, Bisphenol F |
| Interactions | HSPA1A, DNAJB1, FKBP5, P38, LC3, APP |
| SciDEX Target | View Target Profile (8 clinical trials) |
| SciDEX Hypotheses | HSP90-Tau Disaggregation Complex Enhancement |
| KG Connections | 731 knowledge graph edges |
| Databases | GeneCardsHPASTRING |