cell 630 words KG: BBB 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

Pericytes in Diabetic Encephalopathy

🧫 Cell Type Info
Cell TypePericytes in Diabetic Encephalopathy
Also Known AsBlood-brain barrier, Neurovascular unit
FunctionsSelective permeability, Immune cell regulation, Metabolite exchange
Key PathwaysTight junction signaling, ABC transporter-mediated efflux, Transcytosis
Associated DiseasesAlzheimer's disease, Stroke, Multiple sclerosis
Related GenesCLDN5, CLAUDIN5
Linked Hypotheses16 hypotheses

Knowledge Graph

Related Hypotheses (8)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
SASP-Mediated Cholinergic Synapse Disruption
Score: 0.56
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.44

Related Analyses (7)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Cell type vulnerability in Alzheimer's Disease (SEA-AD data)
neurodegeneration · failed

Related Experiments (3)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
s:** - Compare uptake with/without magnetic particles using
falsification · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40

Knowledge Graph (12 edges)

BBB co_discussed BLOOD-BRAIN BARRIER
BBB co_discussed ENDOTHELIAL
BBB co_discussed STROKE
BBB co_discussed CLDN5
BBB co_discussed BECN1
BBB co_discussed MMP2
BBB co_discussed MMP9
BBB co_discussed PERICYTE
BBB co_discussed PERICYTES
BBB co_discussed HIPPOCAMPUS