disease 1,620 words KG: ent-dise-48730064 2026-03-28
cbskind:diseasesection:diseasesneuropsychiatryemotional-lability
Contents

Pseudobulbar Affect and Emotional Lability in Corticobasal Syndrome

Disease Info
Involuntary cryingEpisodes of crying without sadness or appropriate trigger
Involuntary laughingEpisodes of laughing without humor or appropriate trigger
Mixed episodesBoth laughing and crying in rapid succession
Triggered episodesOften provoked by minor stimuli (e.g., slight frustration)
DurationTypically seconds to minutes
AwarenessPatients often retain insight during episodes
DatabasesOMIMOrphanetClinicalTrialsPubMed

Knowledge Graph

Related Hypotheses (3)

Purinergic Signaling Polarization Control
Score: 0.55
Mechanosensitive Ion Channel Reprogramming
Score: 0.51
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.46

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (15)

Yoga Therapy for Neurodegeneration
therapeutic · Pages share 3 hypotheses
YAP/TEAD Pathway Modulators for Neurodegeneration
therapeutic · Pages share 3 hypotheses
Wnt Signaling Modulators for Neurodegeneration
therapeutic · Pages share 3 hypotheses
vitamin-d-therapy-neurodegeneration
therapeutic · Pages share 3 hypotheses
Vitamin B Complex Therapy for Neurodegeneration
therapeutic · Pages share 3 hypotheses