disease 1,620 words KG: ent-dise-48730064
Contents

Pseudobulbar Affect and Emotional Lability in Corticobasal Syndrome

Disease Info
Involuntary cryingEpisodes of crying without sadness or appropriate trigger
Involuntary laughingEpisodes of laughing without humor or appropriate trigger
Mixed episodesBoth laughing and crying in rapid succession
Triggered episodesOften provoked by minor stimuli (e.g., slight frustration)
DurationTypically seconds to minutes
AwarenessPatients often retain insight during episodes
DatabasesOMIMOrphanetClinicalTrialsPubMed

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

OMIMMeSHWikipedia

Related Hypotheses (3)

Purinergic Signaling Polarization Control
Score: 0.71
Mechanosensitive Ion Channel Reprogramming
Score: 0.70
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
Metabolic reprogramming in neurodegenerative disease
neurodegeneration · completed

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (15)

Alpha-Synuclein PET Imaging and Biomarker Advances
biomarker · Pages share 3 hypotheses
Alpha-Synuclein Seeding Assays (RT-QuIC and PMCA)
biomarker · Pages share 3 hypotheses
Blood-Based Biomarkers for Neurodegeneration
biomarker · Pages share 3 hypotheses
Blood p-Tau181 and p-Tau217 Elevated in Systemic Amyloi
biomarker · Pages share 3 hypotheses
CSF Biomarkers for Corticobasal Syndrome and Progressiv
biomarker · Pages share 3 hypotheses

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.