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entity 636 words KG: C9orf72
Contents

C9orf72 Protein (Chromosome 9 Open Reading Frame 72)

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Related Hypotheses (20)

PARP1 Inhibition Therapy
Score: 0.74Senescence-Associated Myelin Lipid Remodeling
Score: 0.73Stress Granule Phase Separation Modulators
Score: 0.72Autophagosome Maturation Checkpoint Control
Score: 0.71Axonal RNA Transport Reconstitution
Score: 0.70Cross-Seeding Prevention Strategy
Score: 0.69R-Loop Resolution Enhancement Therapy
Score: 0.68Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67Arginine Methylation Enhancement Therapy
Score: 0.65Nucleolar Stress Response Normalization
Score: 0.65Glycine-Rich Domain Competitive Inhibition
Score: 0.64Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.62Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62Low Complexity Domain Cross-Linking Inhibition
Score: 0.62Trinucleotide Repeat Sequestration via CRISPR-Guided RNA Tar
Score: 0.61Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56Lysosomal Membrane Repair Enhancement
Score: 0.54Cryptic Exon Silencing Restoration
Score: 0.53Vocal Cord Neuroplasticity Stimulation
Score: 0.52

Related Analyses (10)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archivedSynaptic pruning by microglia in early AD
neurodegeneration · archivedDigital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archivedSenolytic therapy for age-related neurodegeneration
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (2)

Mechanism: C9orf72 Hexanucleotide Repeat Expansion in ALS/FT
validation · proposed · Score: 0.40C9orf72 Phenotype Divergence: ALS vs FTD Mechanism Study
clinical · proposed · Score: 0.40

See Also (5)

ABCA7 (Redirect)
redirect · KG edge: associated_withACTB Gene
gene · KG edge: activatesPackard Center for ALS Research
institution · KG edge: activatesActin Cytoskeleton Dynamics in Neurodegeneration
mechanism · KG edge: co_discussedAging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: co_discussed

Knowledge Graph (12 edges)

C9orf72 regulates MMP9
C9orf72 causes Frontotemporal dementia
C9orf72 causes lysosomal dysfunction
C9orf72 regulates TDP-43
CEREBELLUM associated_with C9orf72
C9orf72 interacts_with WDR41
C9orf72 involved_in Autoimmune Response
C9orf72 expressed_in presynaptic terminals
C9orf72 regulates dendritic arborization
C9orf72 expressed_in cerebellum

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