| Gene Symbol | GABRB3 |
| Aliases | GABA-A receptor beta3 subunit |
| Chromosome | 15q12 |
| Protein Type | Receptor |
| Function | is a critical component of many GABA-A receptor subtypes, including the predominant benzodiazepine-sensitive receptors in the thalamus and cortex. |
| Primary Expression | Brain (thalamus, cortex, hippocampus), widespread CNS |
| Molecular Weight | 54 kDa |
| Amino Acids | 473 aa |
| UniProt ID | P28472 |
| OMIM | 137192 |
| GeneCards | GABRB3 |
| Human Protein Atlas | GABRB3 |
| Genomic Coordinates | chr15:26,700,000-27,100,000 (GRCh38) |
| Gene Length | ~250 kb |
| Number of Exons | 10 coding exons |
| Associated Diseases | neurodegeneration |
| Interactions | MAPT, PSEN1, SCARB2, TFAM, TREM2, UCHL1 |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |