gene 757 words KG: ent-gene-adb197b4
Contents

KCNQ2

🧬 Gene Info
Gene SymbolKCNQ2
AliasesKv7.2
Chromosome20q13.33
Functionis a non-inactivating K+ current that activates at voltages near the threshold for action potential firing.
Primary ExpressionBrain (neurons throughout forebrain, highest in cortex, hippocampus, brainstem)
Molecular Weight95 kDa
Amino Acids844 aa
UniProt IDO43726
NCBI Gene ID3785
Ensembl IDENSG00000155085
OMIM121200
GeneCardsKCNQ2
Human Protein AtlasKCNQ2
Associated DiseasesAging
InteractionsCANCER, EGFR, ERK, RUNX1
KG Connections66 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

APOE-Dependent Autophagy Restoration
Score: 0.89
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73
Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69
Hypocretin-Neurogenesis Coupling Therapy
Score: 0.69
Optogenetic Control of Mitochondrial Transfer Networks
Score: 0.48

Related Analyses (12)

Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Mitochondrial transfer between neurons and glia
neurodegeneration · completed
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed

Related Experiments (5)

AAV-LRRK2 IND-Enabling Study Design
clinical · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Epigenetic Dysregulation Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.40
Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (6)

DHX9 — DEAH-Box Helicase 9
gene · KG edge: therapeutic_target
EGFR — Epidermal Growth Factor Receptor
gene · KG edge: activates
HDAC2 Gene
gene · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: regulates
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: causes

Knowledge Graph (4 edges)

h-b6167641 targets ent-gene-adb197b4
ent-gene-adb197b4 targeted_by h-b6167641
ent-gene-adb197b4 data_in benchmark_ot_ad_answer_key:KCNQ2
benchmark_ot_ad_answer_key:KCNQ2 data_in ent-gene-adb197b4

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