RUNX1

Understanding Entity Pages

This page aggregates everything SciDEX knows about RUNX1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

RUNX1 is a concept in neurodegeneration research. Key relationships include: activates, associated with, regulates. Associated with Als, Alzheimer's disease, Cancer. Connected to 51 entities in the SciDEX knowledge graph.

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graph TD
    RUNX1["<b>RUNX1</b>"]
    RUNX1 -->|"regulates"| osteoblastogenesis["osteoblastogenesis"]
    RUNX1 -.biomarker for.-> Alzheimer_s_disease["Alzheimer's disease"]
    RUNX1 -->|"target for"| Leukemia["Leukemia"]
    RUNX1 -->|"target for"| Als["Als"]
    RUNX1 -->|"activates"| Tumor["Tumor"]
    RUNX1 -->|"regulates"| Ms["Ms"]
    RUNX1 -->|"activates"| Cancer["Cancer"]
    RUNX1 -->|"activates"| Cardiovascular["Cardiovascular"]
    RUNX1 -->|"activates"| HDAC2["HDAC2"]
    RUNX1 -->|"activates"| Tgf__["Tgf-Beta"]
    BCL_2["BCL-2"] -->|"target for"| RUNX1
    ETV6["ETV6"] -->|"activates"| RUNX1
    KMT2A["KMT2A"] -->|"target for"| RUNX1
    KCNQ3["KCNQ3"] -->|"activates"| RUNX1
    EGFR["EGFR"] -->|"activates"| RUNX1
    KCNQ2["KCNQ2"] -->|"activates"| RUNX1
    MECP2["MECP2"] -->|"regulates"| RUNX1
    ERK["ERK"] -->|"activates"| RUNX1
    GENES["GENES"] -->|"activates"| RUNX1
    ANG["ANG"] -->|"activates"| RUNX1
    NRP1["NRP1"] -->|"activates"| RUNX1
    APOE["APOE"] -->|"activates"| RUNX1