gene 1,437 words KG: PFN1
Contents

PFN1 — Profilin 1

🧬 Gene Info
Gene SymbolPFN1
Full NameProfilin 1
Chromosome17p13.3
Protein FamilyProfilin family
Functionregulating cytoskeletal dynamics
Molecular Weight15 kDa
Amino Acids140 aa
Exons4
PathwaysChaperone
UniProt ID[P07737](https://www.uniprot.org/uniprot/P07737)
Ensembl IDENSG00000108518
OMIM176610
GeneCardsPFN1
Human Protein AtlasPFN1
Actin-binding siteInteracts with G-actin (monomeric actin)
Associated DiseasesAls, disease, neurodegeneration
InteractionsALS, DNAJB6
SciDEX HypothesesProfilin-1 Cytoskeletal Checkpoint Enhancement
KG Connections29 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Profilin-1 Cytoskeletal Checkpoint Enhancement
Score: 0.55

Knowledge Graph (12 edges)

DNAJB6 activates PFN1
GAIN associated_with PFN1
PFN1 associated_with GAIN
PFN1 activates DNAJB6
PFN1 implicated_in protein misfolding
DNAJB6 co_expressed_with PFN1
PFN1 associated_with neurodegeneration
CXCL10 co_associated_with PFN1
h-cd49366c targets PFN1
PFN1 associated_with ALS

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