| Gene Symbol | PFN1 |
| Full Name | Profilin 1 |
| Chromosome | 17p13.3 |
| Protein Family | Profilin family |
| Function | regulating cytoskeletal dynamics |
| Molecular Weight | 15 kDa |
| Amino Acids | 140 aa |
| Exons | 4 |
| Pathways | Chaperone |
| UniProt ID | [P07737](https://www.uniprot.org/uniprot/P07737) |
| Ensembl ID | ENSG00000108518 |
| OMIM | 176610 |
| GeneCards | PFN1 |
| Human Protein Atlas | PFN1 |
| Actin-binding site | Interacts with G-actin (monomeric actin) |
| Associated Diseases | Als, Neurodegeneration, disease |
| Interactions | DNAJB6, ALS |
| SciDEX Hypotheses | Profilin-1 Cytoskeletal Checkpoint Enhancement |
| KG Connections | 35 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |