| Gene Symbol | ADORA1 |
| Full Name | Adenosine A1 Receptor |
| Chromosome | 1q32.1 |
| Function | encodes a 326-amino acid protein that is widely expressed throughout the central and peripheral nervous systems. |
| Amino Acids | 326 aa |
| Pathways | Epigenetic, Synaptic Plasticity |
| GeneCards | ADORA1 |
| Human Protein Atlas | ADORA1 |
| Region | Function |
| 5' UTR | Contains upstream open reading frames (uORFs) that regulate translation |
| Coding sequence | Seven transmembrane domains with ligand-binding pocket |
| 3' UTR | Contains miRNA binding sites |
| Promoter | Hypoxia and inflammation response elements |
| Target | Effect |
| Adenylyl cyclase | Inhibition |
| Associated Diseases | Alzheimer's disease, Epilepsy |
| Known Drugs/Compounds | Caffeine |
| Interactions | TAU, MEF2C, ALZHEIMER, LCN2, ALZHEIMER'S DISEASE, ASTROCYTE |
| KG Connections | 36 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |