gene 1,361 words KG: ANKRD11 2026-03-27
kind:genesection:genesstate:published
Contents

ANKRD11 — Ankyrin Repeat Domain 11

🧬 Gene Info
Gene SymbolANKRD11
Full NameANKRD11 — Ankyrin Repeat Domain 11
Chromosome16q24.3
Protein TypeGene
Function### Transcriptional Regulation
Primary Expressionthe brain and has been implicated in neurodevelopment and neurodegeneration
Molecular Weight256 kDa
Amino Acids556 aa
Exons13
NCBI Gene IDSearch NCBI
GeneCardsANKRD11
Human Protein AtlasANKRD11
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (6)

Dual-Domain Antibodies with Engineered Fc-FcRn Affinity Modu
Score: 0.57
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.46
Glycine-Rich Domain Competitive Inhibition
Score: 0.43

Related Analyses (5)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · completed

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (8)

Packard Center for ALS Research
institution · KG edge: contributes_to
SMC3 - Structural Maintenance of Chromosomes 3
gene · KG edge: associated_with
SMC1A
gene · KG edge: associated_with
RAD21 — Cohesin Complex Component in Neurodegeneration
gene · KG edge: associated_with
NIPBL - Nipped-B Like (Cohesin Loader)
gene · KG edge: associated_with

Knowledge Graph (9 edges)

ANKRD11 associated_with NIPBL
ANKRD11 associated_with HDAC8
ANKRD11 associated_with SMC3
ANKRD11 contributes_to BRD4
ANKRD11 associated_with RAD21
ANKRD11 contributes_to Als
ANKRD11 data_in benchmark_ot_ad_answer_key:ANKRD11
SMC1A associated_with ANKRD11
benchmark_ot_ad_answer_key:ANKRD11 data_in ANKRD11