| Gene Symbol | HDAC8 |
| Full Name | HDAC8 |
| Chromosome | Xq13.1 |
| Protein Type | Gene |
| Function | encodes a zinc-dependent class I histone deacetylase enzyme that plays a critical role in epigenetic regulation of gene expression. |
| Primary Expression | various tissues, with significant expression in the brain where it regulates chromatin structure and gene transcription essential for neuronal develop |
| Molecular Weight | 42 kDa |
| Amino Acids | 377 aa |
| Exons | 14 |
| Pathways | NF-κB, NF-κB pathway |
| NCBI Gene ID | Search NCBI |
| GeneCards | HDAC8 |
| Human Protein Atlas | HDAC8 |
| Associated Diseases | Als, Alzheimer |
| Interactions | HDAC3, HDAC1, HDAC2, NEK1, Rb, BAX |
| KG Connections | 146 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |