| Gene Symbol | HES5 |
| Full Name | Hairy and Enhancer of Split 5 |
| Chromosome | 1p36.32 |
| Protein Family | HES family (bHLH transcription factor) |
| Protein Type | Transcription Factor |
| Function | is a basic helix-loop-helix (bHLH) transcription factor that functions as a transcriptional repressor and serves as a key effector of the Notch signaling pathway. |
| Primary Expression | the ventricular and subventricular zones, where neural stem cells reside |
| Amino Acids | 199 aa |
| Pathways | Notch signaling, Notch |
| UniProt ID | [Q5JT76](https://www.uniprot.org/uniprot/Q5JT76) |
| Ensembl ID | ENSG00000197921 |
| OMIM | 604527 |
| GeneCards | HES5 |
| Human Protein Atlas | HES5 |
| Subventricular zone (SVZ) | Neural stem cells |
| Associated Diseases | neurodegeneration |
| Interactions | C-FOS, CYTOKINES, DEPRESSION, FOS, IFN, IL-6 |
| KG Connections | 24 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!