| Gene Symbol | LGI1 |
| Full Name | Leucine-Rich Glioma Inactivated 1 |
| Chromosome | 10q24.3 |
| Protein Type | Receptor |
| Function | encodes a secreted neuronal protein that serves as a critical regulator of synaptic transmission and neuronal excitability. |
| Primary Expression | brain with potential roles in neuronal function |
| Subcellular Localization | - **Synaptic terminals**: Secreted at both presynaptic and postsynaptic sites |
| Molecular Weight | 63 kDa |
| Amino Acids | 557 aa |
| UniProt ID | O75771 |
| NCBI Gene ID | 2709 |
| Ensembl ID | ENSG00000162711 |
| OMIM | 604619 |
| GeneCards | LGI1 |
| Human Protein Atlas | LGI1 |
| Associated Diseases | neurodegeneration |
| KG Connections | 11 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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