| Gene Symbol | PLEC |
| Full Name | Plectin |
| Chromosome | 8q24.3 |
| Protein Family | Plakin family, cytolinker proteins |
| Function | encodes a protein of approximately 500 kDa, making it one of the largest known proteins. |
| Primary Expression | dopaminergic neurons
- Supports neuronal cytoskeletal integrity
- Altered expression in PD |
| Molecular Weight | 500 kDa |
| Gene Type | Protein-coding |
| UniProt ID | Q15120 |
| NCBI Gene ID | 5339 |
| Ensembl ID | ENSG00000109189 |
| OMIM | 162284 |
| GeneCards | PLEC |
| Human Protein Atlas | PLEC |
| Encoded Protein | Plectin |
| Associated Diseases | ALS, Alzheimer's Disease |
| Interactions | ASTROCYTES, RNA, ALZHEIMER, Proteins, C1Q |
| KG Connections | 66 knowledge graph edges |
| Databases | GeneCardsHPASTRING |