gene 824 words KG: RAB12 2026-03-24
kind:genesection:genesstate:published
Contents

RAB12 Gene

🧬 Gene Info
Gene SymbolRAB12
Full NameRAB12, Member RAS Oncogene Family
Chromosome18p11.22
FunctionRAB12 encodes a member of the RAB family of small GTPases, which are key regulators of intracellular vesicle trafficking.
Primary Expressionthe substantia nigra, and dysregulated RAB12 function may contribute to:
Molecular Weight24 kDa
PathwaysmTOR, mtor
UniProt IDQ96CM8
NCBI Gene ID157556
Ensembl IDENSG00000139433
GeneCardsRAB12
Human Protein AtlasRAB12
StrategyApproach
[Autophagy](/entities/autophagy) enhancementSmall molecules to enhance RAB12-mediated autophagy
Gene therapyAAV-mediated RAB12 overexpression
Associated Diseasesneurodegeneration
InteractionsLRRK2, RAB10, JIP4
KG Connections12 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph