gene 973 words KG: RAB10 2026-03-22
kind:genesection:genesstate:published
Contents

rab10 Gene

🧬 Gene Info
Gene SymbolRAB10
Full NameRAB10, Member RAS Oncogene Family
Chromosome2p22.3
Protein FamilyRab GTPase family
FunctionRAB10 encodes a member of the Rab GTPase family involved in intracellular membrane trafficking
Subcellular LocalizationRAB10 localizes to:
Molecular Weight23 kDa
ExonsMultiple protein-coding exons spanning approximately 15 kb
PathwaysAutophagy, Mitophagy, autophagy pathway, mitophagy
UniProt IDQ9Y2P8
NCBI Gene ID10890
Ensembl IDENSG00000100705
OMIM-
GeneCardsRAB10
Human Protein AtlasRAB10
Associated DiseasesALS, Parkinson
InteractionsPARK16, LRRK2, RAB29, RAB7A, PAK1, CDC42
KG Connections115 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (8)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Membrane Cholesterol Gradient Modulators
Score: 0.52
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.49
APOE Isoform Expression Across Glial Subtypes
Score: 0.48
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Optineurin
protein · KG edge: activates
LRRK2 G2019S Transgenic Mouse Model
model · KG edge: associated_with
Mitophagy Receptor Pathway in Neurodegeneration
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: therapeutic_target

Knowledge Graph (12 edges)

RAB10 associated_with RAB3A
RAB10 activates PARK16
RAB10 associated_with RAB11B
RAB10 associated_with RAB3C
RAB10 associated_with RAB5A
RAB10 associated_with RAB5
RAB10 associated_with RAB27B
RAB10 inhibits LRRK2
RAB10 associated_with RAB3B
RAB10 associated_with RAB4B