gene 2,779 words KG: SCA7 2026-03-26
kind:genesection:genesstate:published
Contents

SCA7 Gene

🧬 Gene Info
Gene SymbolSCA7
Full NameATXN7 (Ataxin-7)
Chromosome3p12
Protein TypeTransferase
Functionis a 892-amino acid protein with several distinct functional domains
Amino Acids892 aa
Exons13
UniProt ID[Q9UQ50](https://www.uniprot.org/uniprotkb/Q9UQ50/entry)
GeneCardsSCA7
Human Protein AtlasSCA7
Associated DiseasesAtaxia
InteractionsATG12
KG Connections16 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (14)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.66
CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
PARP1 Inhibition Therapy
Score: 0.58
Matrix Stiffness Normalization via Targeted Lysyl Oxidase In
Score: 0.51

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Spinocerebellar Ataxia (SCA) Disease-Modifying Therapy Devel
validation · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (12 edges)

SCA7 regulates SPG7
SCA7 co_expressed_with SPG7
SCA7 regulates neurodegeneration
SCA7 therapeutic_target NEURODEGENERATION
SCA7 causes NEURODEGENERATIVE DISEASES
SCA7 associated_with Ataxia
SCA7 therapeutic_target Neurodegeneration
SCA7 expressed_in neurons
SCA7 participates_in autophagy pathway
SCA3 regulates SCA7